Home Page > Suppliers > ZenBio
 
ZenBio

Welcome to ZenBio - Distributed in the UK & Europe by Caltag Medsystems

ZenBio offers research partners a unique "cells and services" model delivering robust cell-based solutions to accelerate the discovery and development of therapies to better the human condition.

ZenBio

They have expanded their product portfolio for global partners in both biomedical research and cosmetics and personal care to include:

  • Human cell-based products, inlcuding fresh apheresis and bone marrow, isolated haematopoetic cells and human platelet lysate
  • ZenComplete™ and ZenSkin™ research solutions platforms
  • Contract research services for outsourcing key projects
  • Cell-based assay development and custom consultations
  • Individualised screening programs (cell-based or biochemical)
  • Cell characterisation and molecular biology services

PMBCs and Plasma Products Sale, up to 75% Off

Caltag Medsystems is the go-to distributor for ZenBio products in the UK & Europe and we are delighted to bring you this time limited promotion offer while stocks last. Please quote ZEN2020 in your order or quotation request.

Please contact our sales and technical team and they will be very happy to assist and provide a quotation: techsupport@caltagmedsystems.co.uk.

The offer is valid until 31st March 2020 and excludes shipping charges.

Full Details

Human Blood Products

ZenBio can provide many different Human blood components to meet your research needs. They have the abilility to collect and process per your specifications or by standard collection methods. Some of their standard products are shown below. If you do not see the specific item that you need listed here, please contact us. We will work with you to provide the materials that fit your research specifications and budget.

*All samples are collected in FDA licensed facility and pathogen tested according to FDA guidelines for the following: HBsAG, Anti-HCV, Anti-HIV-1/2, HIV-1 RNA, HBV DNA, HCV RNA, Syphilis.

Products include the following:

ZenBio Products
  • LeukoPaks
  • Mobilised LeukoPaks
  • Fresh Bone Marrow
  • Human Serum
  • Recovered Plasma
  • Source Plasma
  • Whole Blood
  • Red Blood Cells
  • Leukocytes (Buffy Coats)
  • Platelet Rich Plasma
  • Platelet Concentrates

Specifications possible for all products:

  • In preservative solutions: ACD, CPD, CPDA-1, Heparin, EDTA, PAXgene® Blood Tube
  • Blood group type-specific
  • Containing hemoglobin AA or AS
  • Specific MCV range
  • Gender, age, or ethnicity specific

Leukocyte specifications possible:

  • Types of leukocyte preparations available:
    • LeukoPaks
    • Mobilised LeukoPaks
    • Buffy coats
    • Isolated cells - fresh or frozen
    • Gender, age, or ethnicity specific

Serum specifications possible:

  • Types of serum available: off-clot serum
  • Single units or pools
  • Gender, age, or ethnicity specific

Plasma specifications possible:

  • Types of plasma available:
    • Heparin anticoagulant
    • Sodium Citrate anticoagulant
    • EDTA anticoagulant
    • ACD anticoagulant
    • platelet-poor
    • platelet-rich
    • Fresh Frozen Plasma
    • Source Plasma
    • Recovered/Outdated plasma
  • Single units or pools
  • Gender, age, or ethnicity specific

Platelet specifications possible:

  • Types of platelets available:
    • recovered platelet-rich plasma
    • platelet concentrates
  • Gender, age, or ethnicity specific

Packed Red Blood Cells

  • Sized for MCV
  • 48-hour turnaround
  • Negative for HBsAg, HIV 1-2, HCV and RPR
  • Blood group specific
  • Gender, age, or ethnicity specific
  • Fresh and outdated

View Blood Products

Human Serum & Animal-Free Growth Supplement

ZenBio is proud to offer several non-animal replacements for Fetal Bovine Serum (FBS): Human Platelet Lysate-(New!), GroPro ready-to-use growth supplement and Human AB Serum.

ZenBio GroPro

ZenBio's NEW! Human Platelet Lysate (HPL) and GroPro are a non-animal derived cell culture growth supplements obtained from human platelets. HPL contains abundant growth factors and cytokines necessary for cell growth and proliferation. Platelet lysate can be used as a replacement for traditional Fetal Bovine (FBS) supplemented cell culture medium. Replacing fetal bovine serum (FBS) with HPL allows for expansion and potential clinical grade production of functional mesenchymal stromal cells by removing the risk of xenogeneic immune reactions and transmission of bovine prion and viral pathogens. Additionally, HPL and GroPro are derived from a renewable source that is not tied to the animal slaughter industry and the price does not fluctuate!

The US FDA is moving towards adopting European guidelines requiring that bovine materials be removed from culturing media for any therapeutic product containing cultured cells, thus making HPL an attractive alternative to the R&D and production/manufacturing processes. All lots are fully tested for pathogens according to FDA guidelines.

  • Fetal Bovine Serum
  • 10X more potent than FBS
  • Stable Pricing
  • Non-Animal Derived
  • Traceability
  • Free of Mycoplasma
  • Lot-to-Lot Consistency
  • Sterile Collection
  • Pool Processing
  • QC Tested in Zen Bio's Cell Production System

View Human Platelet Lysate

ZenBio - Chart: Substitution of HPL for FBS

Human Cells

ZenBio was founded on the premise that researchers have more important work at hand that struggling with procuring tissue and isolating cells. Since their founding in 1995 they have established a robust tissue procurement network and world class cell isolation technologies in order to simplify research that requires primary cell systems. Our tissue collection and cell isolation procedures are all IRB approved and we have a rigorous quality control system that helps insure only the highest quality cells and media are shipped to our customers.

They have multiple cell systems currently in development so if you do not see a cell system that meets your needs, let us know and we will work to accommodate your request.

Currently, the following cell types are available:

Human Exosomes

ZenBio - Human Exosomes

ZenBio human pre-adipocytes (adipose derived adult stem cells) and placental mesenchymal stem cells (MSC) are characterized by their self-renewing capacity and ability to differentiate into chondrocytes, adipocytes, and osteocytes. This makes them attractive starting materials for tissue engineering and regenerative medicine applications.

Since few transplanted cells persist in vivo, the beneficial effects of cell therapy may lie in the secreted factors being the active component of this treatment. A key part of paracrine secretion is Exosomes, which are membrane vesicles that are stored intracellularly in endosomal compartments and are secreted when these structures fuse with the cell plasma membrane.

  • Exosomes contain protein, DNA, and RNA, thus making them an attractive vector of paracrine signals delivered by stem cells.
  • Exosomes may also be "loaded" with predetermined proteins and nucleic acid to achieve a desired effect.
  • Exosomes can be stored as an "off-the-shelf" product having the potential for circumventing many of the limitations of viable cells for therapeutic applications in regenerative medicine.
  • In vitro, exosomes from pre-adipocytes stimulate cell proliferation in a wound healing model.
  • In vivo, adipose-graft derived exosomes have been shown to be a promising tool for skin repair and remodeling.

Quality Control: All cells have been screened negative for HIV-1, HIV-2, Hep-B, Hep-C and Syphilis. All isolated and concentrated exosomes undergo includes Particle mean diameter, Protein concentration, RNA concentration and Concentration of particles/ml.

View Exosome Products

Extra Cellular Matrix (ECM) Coated Cell Culture Plastics

ZenBio - Collagen I

Collagen I - ZenBio is proud to offer collagen I coated Tissue Culture ware. Collagen is one of the more abundant components of the extracellular matrix proteins and the major constituent that gives strength to connective tissue and found in dermis, bone, ligament and tendons. A key role for collagens is to provide a scaffold for cell attachment differentiation, proliferation, and migration. Numerous studies have shown that anchorage dependent cells grown on collagen have increased proliferation, acquire higher cell densities, and require lower serum and growth factor concentrations. We only use high quality and purity collagen I derived from rat tail.

  • Ready to use right from the package
  • Available in multiple formats
  • High-quality, consistent coating of rat tail collagen I for culturing primary cells
  • Convenient room temperature storage
  • Cost Effective
Material Flask: polystyrene
Plates: polystyrene
Cap: polyethylene
Vent: Hydrophobic
Sterile Yes
Shipping Room Temperature
Storage 4-30°C; Shelf life: 6 months from date of shipment
Cap Vented
Neck Canted

View Coated Plasticware

Cell Culture Media

All ZenBio media are performance tested for sterility and functionality in ZenBio cells. These media formulations are the results of years of experience in providing nutrients for optimal cell culture growth in research and manufacturing. The goal is to provide customers with consistent high-quality media at the best prices, allowing researchers the freedom and convenience to optimize their own systems, while removing one more variable from their research efforts.

Quality Control

In order to maintain consistent quality control all media are manufactured under strict compliance to written operating procedures. This provides the same quality product and reliability from lot to lot.

Formulations

Media formulations are readily available and can be ordered at anytime with very short delivery times. Media can be ordered in various formulations:

  • Basal (without antibiotics)
  • Phenol-Red Free
  • Without serum
  • Serum Free formulation (ZB Free)

View Media Available

Cosmeceutical Kits

ZenBio offers four research kits to test compounds for their potential use in cosmeceutical testing for antioxidant, cellulite, or wrinkle treatments. The cellulite and wrinkle assays allow scientists to target the subcutaneous fat layer to alter the outward appearance of skin. The antioxidant assays determine the total antioxidant activity of potential anti-aging treatments.

ZenBio offers two research kits to test compounds for their potential use in as cellulite or wrinkle treatments. The assays allow scientists to target the subcutaneous fat layer to alter the outward appearance of skin.

  • ABTS Antioxidant Assay Kit
    The ZenBio ABTS Antioxidant Assay Kit can be used to determine the total antioxidant capacity of biological fluids, cells, and tissue. It can also be used to assay the antioxidant activity of naturally occurring or synthetic compounds for use as dietary supplements, topical protection, and therapeutics
  • Anti-Cellulite Screening
    This kit provides a tool to study chemical compounds that may influence lipolysis in cultured human adipocytes. This kit specifically measures both the non-esterified fatty acids (free fatty acids) and the glycerol released by the breakdown of triglyceride.
  • Anti-Wrinkle Screening
    This kit is designed to test compounds as potential PPAR. agonists. It is our experience that the PPAR. agonist used as the Positive Control sufficiently stimulates human adipocyte differentiation after 7 days of treatment.
  • ORAC Antioxidant Assay Kit
    The ZenBio ORAC (Oxygen Radical Absorbance Capacity) Antioxidant Assay Kit can be used to determine the total antioxidant capacity of biological fluids, cells, and tissue. It can also be used to assay the antioxidant activity of naturally occurring or synthetic compounds for use as dietary supplements, topical protection, and therapeutics

Please do contact us if you require any products which are not listed, as we may be able to provide a custom product.

Select:

  • Suppliers
  • Suppliers
  • Products