NSJ Bioreagents

TrkA Antibody (NTRK1)

Product Code:
 
NSJ-R31269
Product Group:
 
Primary Antibodies
Supplier:
 
NSJ Bioreagents
Host Type:
 
Rabbit
Antibody Isotype:
 
Rabbit IgG
Antibody Clonality:
 
Polyclonal
Regulatory Status:
 
RUO
Target Species:
  • Mouse
  • Rat
Application:
 
Western Blot (WB)
Storage:
 
After reconstitution, the TrkA antibody can be stored for up to one month at 40. For long-term, aliquot and store at -200. Avoid repeated freezing and thawing.
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Western blot testing of TrkA antibody and Lane 1: rat brain; 2: mouse brain tissue lysate. Observed molecular weight: 85~140 kDa depending on glycosylation level.
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Western blot testing of TrkA antibody and Lane 1: rat brain; 2: mouse brain tissue lysate. Observed molecular weight: 85~140 kDa depending on glycosylation level.

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CodeSizePrice
NSJ-R31269-100ug100 ug£535.00
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Further Information

Application Details :
Western blot: 0.5-1ug/ml
Application Note:
The stated application concentrations are suggested starting amounts. Titration of the TrkA antibody may be required due to differences in protocols and secondary/substrate sensitivity.
Description:
Neurotrophic tyrosine kinase receptor type 1, also called TrkA, is a protein that in humans is encoded by the NTRK1 gene. The gene encodes the neurotrophic tyrosine kinase-1 receptor and belongs to a family of nerve growth factor receptors whose ligands include neurotrophins. This gene is mapped to 1q23.1. This kinase is a membrane-bound receptor that, upon neurotrophin binding, phosphorylates itself and members of the MAPK pathway. The presence of this kinase leads to cell differentiation and may play a role in specifying sensory neuron subtypes. Mutations in this gene have been associated with congenital insensitivity to pain, anhidrosis, self-mutilating behavior, mental retardation and cancer.
Format :
Antigen affinity purified
Formulation :
0.5mg/ml if reconstituted with 0.2ml sterile DI water
Immunogen:
An amino acid sequence from the N-terminus of mouse TrkA (LYVENQQHLQRLEFEDLQGL) was used as the immunogen for this TrkA antibody.
Limitation:
This TrkA antibody is available for research use only.
Purity:
Antigen affinity
Species Reactivity :
Mouse, Rat
Uniprot #:
Q3UFB7