NSJ Bioreagents

Lamin B2 Antibody

Product Code:
 
NSJ-R30719
Product Group:
 
Primary Antibodies
Supplier:
 
NSJ Bioreagents
Host Type:
 
Rabbit
Antibody Isotype:
 
Rabbit IgG
Antibody Clonality:
 
Polyclonal
Regulatory Status:
 
RUO
Target Species:
  • Human
  • Mouse
  • Rat
Applications:
  • Immunohistochemistry- Frozen Section (IHC-F)
  • Immunohistochemistry- Paraffin Embedded (IHC-P)
  • Western Blot (WB)
Storage:
 
The lyophilized Lamin B2 antibody can be stored at 40. After reconstitution, aliquot and store at -200. Avoid repeated freezing and thawing.
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Western blot testing of Lamin B2 antibody and Lane 1: HeLa; 2: U87 cell lysate~
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IHC-P: Lamin B2 antibody testing of rat intestine tissue
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Western blot testing of Lamin B2 antibody and Lane 1: HeLa; 2: U87 cell lysate~
IHC-P: Lamin B2 antibody testing of rat intestine tissue

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NSJ-R30719-100ug100 ug£535.00
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Further Information

Application Details :
Western blot: 0.5-1ug/ml,Immunohistochemistry (FFPE): 0.5-1ug/ml,Immunohistochemistry (Frozen): 0.5-1ug/ml
Application Note:
Titration of the Lamin B2 antibody may be required due to differences in protocols and secondary/substrate sensitivity.
Description:
Lamin B2, also called LMNB2, is a protein associated with laminopathies. The LMNB2 gene is mapped to the G-negative subtelomeric band p13.3 of chromosome 19 by in situ hybridization. Model organisms have been used in the study of Lamin B2 function. A conditional knockout mouse line, called Lmnb2, was generated as part of the International Knockout Mouse Consortium program-a high-throughput mutagenesis project to generate and distribute animal models of disease to interested scientists. A highly sensitive procedure about mapping the start site of DNA replication in a 13.7-kb region of human chromosome 19 coding for lamin B2 is developed for the identification of the origin of bidirectional DNA synthesis in single-copy replicons of mammalian cells.
Format :
Antigen affinity purified
Formulation :
0.5mg/ml if reconstituted with 0.2ml sterile DI water
Immunogen:
Amino acids 580-597 (EEDLFHQQGDPRTTSRGC) were used as the immunogen for this Lamin B2 antibody (100% homologous in human, mouse and rat).
Limitation:
This Lamin B2 antibody is available for research use only.
Purity:
Antigen affinity
Species Reactivity :
Human, Mouse, Rat
Uniprot #:
Q03252