NSJ Bioreagents

IFITM1 Antibody

Product Code:
 
NSJ-R30277
Product Group:
 
Primary Antibodies
Supplier:
 
NSJ Bioreagents
Host Type:
 
Rabbit
Antibody Isotype:
 
Rabbit IgG
Antibody Clonality:
 
Polyclonal
Regulatory Status:
 
RUO
Target Species:
 
Human
Applications:
  • Immunohistochemistry- Frozen Section (IHC-F)
  • Immunohistochemistry- Paraffin Embedded (IHC-P)
  • Western Blot (WB)
Storage:
 
After reconstitution, the IFITM1 antibody can be stored for up to one month at 40. For long-term, aliquot and store at -200. Avoid repeated freezing and thawing.
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Western blot testing of IFITM1 antibody and Lane 1: SW620; 2: CEM cell lysate~
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IHC-P: IFITM1 antibody testing of human intestinal cancer tissue
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Western blot testing of IFITM1 antibody and Lane 1: SW620; 2: CEM cell lysate~
IHC-P: IFITM1 antibody testing of human intestinal cancer tissue

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NSJ-R30277-100ug100 ug£535.00
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Further Information

Application Details :
Western blot: 0.5-1ug/ml,Immunohistochemistry (FFPE): 0.5-1ug/ml,Immunohistochemistry (Frozen): 0.5-1ug/ml
Application Note:
The stated application concentrations are suggested starting amounts. Titration of the IFITM1 antibody may be required due to differences in protocols and secondary/substrate sensitivity.
Description:
Interferon-induced Transmembrane Protein 1(IFITM1), also called Interferon-induced Protein 17(IFI17). IFITM1 activity is required for primordial germ cells(PGCs) transit from the mesoderm into the endoderm, and that it appears to act via a repulsive mechanism, such that PGCs avoid Ifitm1-expressing tissues. It is mapped to Chr.11 and belongs to the family of interferon-induced transmembrane proteins(Ifitm/mil/fragilis), which encodes cell surface proteins that may modulate cell adhesion and influence cell differentiation. Interferon-inducible membrane proteins of approximately 17 kDa have been suggested to play a role in the antiproliferative activity of interferons based on their pattern of induction in interferon-sensitive and -resistant cell lines and the ability of a membrane fraction enriched in 17-kDa proteins to inhibit cell growth.
Format :
Antigen affinity purified
Formulation :
0.5mg/ml if reconstituted with 0.2ml sterile DI water
Immunogen:
An amino acid sequence from the N-terminus of human IFITM1 (MHKEEHEVAVLGPPPST) was used as the immunogen for this IFITM1 antibody.
Limitation:
This IFITM1 antibody is available for research use only.
Purity:
Antigen affinity
Species Reactivity :
Human
Uniprot #:
P13164