NSJ Bioreagents

HIF-3 alpha Antibody

Product Code:
 
NSJ-R31264
Product Group:
 
Primary Antibodies
Supplier:
 
NSJ Bioreagents
Host Type:
 
Rabbit
Antibody Isotype:
 
Rabbit IgG
Antibody Clonality:
 
Polyclonal
Regulatory Status:
 
RUO
Target Species:
  • Human
  • Rat
Application:
 
Western Blot (WB)
Storage:
 
After reconstitution, the HIF-3 alpha antibody can be stored for up to one month at 40. For long-term, aliquot and store at -200. Avoid repeated freezing and thawing.
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Westrn blot testing of HIF-3 alpha antibody and rat brain tissue lysate. Expected/observed size ~72KD
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Westrn blot testing of HIF-3 alpha antibody and rat brain tissue lysate. Expected/observed size ~72KD

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NSJ-R31264-100ug100 ug£535.00
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Further Information

Application Details :
Western blot: 0.5-1ug/ml
Application Note:
The stated application concentrations are suggested starting amounts. Titration of the HIF-3 alpha antibody may be required due to differences in protocols and secondary/substrate sensitivity.
Description:
Hypoxia-inducible factor 3 alpha, also called MOP7, is a protein that in humans is encoded by the HIF3A gene. This gene involved in adaptive response to hypoxia. HIF3a suppresses hypoxia-inducible expression of HIF1a and HIF2a. It binds to core DNA sequence 5'-TACGTG-3' within the hypoxia response element(HRE) of target gene promoters. The complex HIF3a-ARNT activates the transcription of reporter genes driven by HRE. This gene functions as an inhibitor of angiogenesis in the cornea.
Format :
Antigen affinity purified
Formulation :
0.5mg/ml if reconstituted with 0.2ml sterile DI water
Immunogen:
An amino acid sequence from the C-terminus of human HIF3A (DDDFQLNASEQLPRAYHR) was used as the immunogen for this HIF-3 alpha antibody.
Limitation:
This HIF-3 alpha antibody is available for research use only.
Purity:
Antigen affinity
Species Reactivity :
Human, Rat
Uniprot #:
Q9Y2N7