NSJ Bioreagents

HEXB Antibody

Product Code:
 
NSJ-R31624
Product Group:
 
Primary Antibodies
Supplier:
 
NSJ Bioreagents
Host Type:
 
Rabbit
Antibody Isotype:
 
Rabbit IgG
Antibody Clonality:
 
Polyclonal
Regulatory Status:
 
RUO
Target Species:
 
Human
Applications:
  • Immunohistochemistry- Paraffin Embedded (IHC-P)
  • Western Blot (WB)
Storage:
 
After reconstitution, the HEXB antibody can be stored for up to one month at 40. For long-term, aliquot and store at -200. Avoid repeated freezing and thawing.
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Western blot testing of HEXB antibody and Lane 1: HeLa; 2: HEPG2 lysate. Predicted/observed size ~63KD
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Western blot testing of HEXB antibody and recombinant human protein (0.5ng)
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IHC-P: HEXB antibody testing of human lung cancer tissue
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Western blot testing of HEXB antibody and Lane 1: HeLa; 2: HEPG2 lysate. Predicted/observed size ~63KD
Western blot testing of HEXB antibody and recombinant human protein (0.5ng)
IHC-P: HEXB antibody testing of human lung cancer tissue

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CodeSizePrice
NSJ-R31624-100ug100 ug£535.00
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Further Information

Application Details :
Western blot: 0.5-1ug/ml,Immunohistochemistry (FFPE): 0.5-1ug/ml
Application Note:
The stated application concentrations are suggested starting amounts. Titration of the HEXB antibody may be required due to differences in protocols and secondary/substrate sensitivity.
Description:
Hexosaminidase beta (HEXB) is an enzyme that in humans is encoded by the HEXB gene. It is mapped to 5q13.3. HEXB is the beta subunit of the lysosomal enzyme beta-hexosaminidase that, together with the cofactor GM2 activator protein, catalyzes the degradation of the ganglioside GM2, and other molecules containing terminal N-acetyl hexosamines. Beta subunit gene mutations lead to Sandhoff disease (GM2-gangliosidosis type II). It has been found that HEXB is a peptidoglycan hydrolase and it is involved in restricting mycobacteria growth even before the onset of adaptive immunity.
Format :
Antigen affinity purified
Formulation :
0.5mg/ml if reconstituted with 0.2ml sterile DI water
Gene ID #:
3074
Immunogen:
Human partial recombinant protein (AA 381-556) was used as the immunogen for this HEXB antibody.
Limitation:
This HEXB antibody is available for research use only.
Purity:
Antigen affinity
Species Reactivity :
Human