NSJ Bioreagents

Cullin 5 Antibody / CUL5

Product Code:
 
NSJ-RQ4333
Product Group:
 
Primary Antibodies
Supplier:
 
NSJ Bioreagents
Host Type:
 
Rabbit
Antibody Isotype:
 
Rabbit IgG
Antibody Clonality:
 
Polyclonal
Regulatory Status:
 
RUO
Target Species:
  • Human
  • Mouse
  • Rat
Applications:
  • Enzyme-Linked Immunosorbent Assay (ELISA)
  • Western Blot (WB)
Storage:
 
After reconstitution, the Cullin 5 antibody can be stored for up to one month at 40. For long-term, aliquot and store at -200. Avoid repeated freezing and thawing.
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Western blot testing of rat 1) brain, 2) spleen, 3) heart, 4) kidney and mouse 5) brain, 6) spleen, 7) heart, 8) kidney and 9) testis lysate with Cullin 5 antibody at 0.5ug/ml. Predicted molecular weight ~91 kDa.
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Western blot testing of rat 1) brain, 2) spleen, 3) heart, 4) kidney and mouse 5) brain, 6) spleen, 7) heart, 8) kidney and 9) testis lysate with Cullin 5 antibody at 0.5ug/ml. Predicted molecular weight ~91 kDa.

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CodeSizePrice
NSJ-RQ4333-100ug100 ug£535.00
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Further Information

Application Details :
Western blot: 0.5-1ug/ml, Direct ELISA: 0.1-0.5ug/ml (human recombinant protein)
Application Note:
Optimal dilution of the Cullin 5 antibody should be determined by the researcher.
Buffer:
Lyophilized from 1X PBS with 2% Trehalose and 0.025% sodium azide
Description:
Cullin-5 is a protein that in humans is encoded by the CUL5 gene. Cul5 inhibits cellular proliferation, potentially through its involvement in the SOCS/ BC-box/ eloBC/ cul5/ RING E3 ligase complex, which functions as part of the ubiquitin system for protein degradation. One study have shown that Cul5 plays a role in Reelin signaling cascade, participating in the DAB1 degradation and thus ensuring the negative feedback mechanism of Reelin signaling during corticogenesis.
Format :
Antigen affinity purified
Formulation :
0.5mg/ml if reconstituted with 0.2ml sterile DI water
Immunogen:
A recombinant human protein corresponding to amino acids A2-D105 was used as the immunogen for the Cullin 5 antibody.
Limitation:
This Cullin 5 antibody is available for research use only.
Purity:
Antigen affinity purified
Species Reactivity :
Human, Mouse, Rat
Uniprot #:
Q93034