NSJ Bioreagents

ANG2 Antibody

Product Code:
 
NSJ-R30139
Product Group:
 
Primary Antibodies
Supplier:
 
NSJ Bioreagents
Host Type:
 
Rabbit
Antibody Isotype:
 
Rabbit IgG
Antibody Clonality:
 
Polyclonal
Regulatory Status:
 
RUO
Target Species:
  • Human
  • Mouse
  • Rat
Application:
 
Immunohistochemistry- Paraffin Embedded (IHC-P)
Storage:
 
After reconstitution, the ANG2 antibody can be stored for up to one month at 40. For long-term, aliquot and store at -200. Avoid repeated freezing and thawing.
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IHC-P: ANG2 antibody testing of human placenta tissue
2 / 3
IHC-P: ANG2 antibody testing of mouse intestine tissue
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IHC-P: ANG2 antibody testing of rat intestine tissue
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IHC-P: ANG2 antibody testing of human placenta tissue
IHC-P: ANG2 antibody testing of mouse intestine tissue
IHC-P: ANG2 antibody testing of rat intestine tissue

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CodeSizePrice
NSJ-R30139-100ug100 ug£535.00
Quantity:
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This product comes from: United States.
Typical lead time: 10-14 working days.
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Further Information

Application Details :
Immunohistochemistry (FFPE): 0.5-1ug/ml
Application Note:
The stated application concentrations are suggested starting amounts. Titration of the ANG2 antibody may be required due to differences in protocols and secondary/substrate sensitivity.
Description:
Angiopoietin 2, also known as ANG2, is a protein that in humans is encoded by the ANGPT2 gene. It is mapped to 8p23.1. ANGPT2 is a naturally occurring antagonist of ANGPT1 that competes for binding to the TIE2 receptor and blocks ANGPT1-induced TIE2 autophosphorylation during vasculogenesis. The encoded protein disrupts the vascular remodeling ability of ANGPT1 and may induce endothelial cell apoptosis. ANGPT2 was significantly increased in plasma and alveolar edema fluid in adults with acute lung injury compared to controls or patients with hydrostatic pulmonary edema, tracheal. ANGPT2 was also significantly increased in neonates with respiratory distress syndrome who developed bronchopulmonary edema. It is also a mediator of epithelial necrosis with an important role in hyperoxic acute lung injury and pulmonary edema.
Format :
Antigen affinity purified
Formulation :
0.5mg/ml if reconstituted with 0.2ml sterile DI water
Gene ID #:
285
Immunogen:
Human partial recombinant protein (AA 19-348) was used as the immunogen for this ANG2 antibody.
Limitation:
This ANG2 antibody is available for research use only.
Purity:
Antigen affinity
Species Reactivity :
Human, Mouse, Rat