NSJ Bioreagents

ACE Antibody [Angiotensin Converting Enzyme]

Product Code:
 
NSJ-R31318
Product Group:
 
Primary Antibodies
Supplier:
 
NSJ Bioreagents
Host Type:
 
Rabbit
Antibody Isotype:
 
Rabbit IgG
Antibody Clonality:
 
Polyclonal
Regulatory Status:
 
RUO
Target Species:
 
Human
Applications:
  • Immunohistochemistry- Paraffin Embedded (IHC-P)
  • Western Blot (WB)
Storage:
 
After reconstitution, the ACE antibody can be stored for up to one month at 40. For long-term, aliquot and store at -200. Avoid repeated freezing and thawing.
1 / 3
IHC-P: ACE antibody testing of human prostate cancer tissue
2 / 3
IHC-P: ACE antibody testing of human placenta tissue
3 / 3
Western blot testing of ACE antibody and (1) HeLa, (2) A549 and (3) 22RV1 lysate. Predicted molecular weight ~170 kDa.
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IHC-P: ACE antibody testing of human prostate cancer tissue
IHC-P: ACE antibody testing of human placenta tissue
Western blot testing of ACE antibody and (1) HeLa, (2) A549 and (3) 22RV1 lysate. Predicted molecular weight ~170 kDa.

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NSJ-R31318-100ug100 ug£535.00
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Further Information

Application Details :
Western blot: 0.5-1ug/ml,Immunohistochemistry (FFPE): 0.5-1ug/ml
Application Note:
The stated application concentrations are suggested starting amounts. Titration of the ACE1 antibody may be required due to differences in protocols and secondary/substrate sensitivity.
Description:
Angiotensin converting enzyme, also called DCP or CD143, is a zinc-containing dipeptidyl carboxypeptidase widely distributed in mammalian tissues and is though to play a critical role in blood pressure regulation. The ACE gene is mapped to 17q23.3. This gene encodes an enzyme involved in catalyzing the conversion of angiotensin I into a physiologically active peptide angiotensin II. Angiotensin II is a potent vasopressor and aldosterone-stimulating peptide that controls blood pressure and fluid-electrolyte balance. This enzyme plays a key role in the renin-angiotensin system. Many studies have associated the presence or absence of a 287 bp Alu repeat element in this gene with the levels of circulating enzyme or cardiovascular pathophysiologies.
Format :
Antigen affinity purified
Formulation :
0.5mg/ml if reconstituted with 0.2ml sterile DI water
Immunogen:
An amino acid sequence from the middle region of human Angiotensin Converting Enzyme 1 (TQARKFDVNQLQNT) was used as the immunogen for this ACE antibody.
Limitation:
This ACE antibody is available for research use only.
Purity:
Antigen affinity
Species Reactivity :
Human
Uniprot #:
P12821