Further Information
Alternate Names/Synonyms:
3-[[[(Phenylamino)thioxomethyl]hydrazono]methyl]-rifamycin
Red powder.
51707-27-8
32160000
liquid
Keep cool and dry.Protect from light.Protect from light when in solution.
InChI=1S/C45H54N4O12S/c1-21-14-13-15-22(2)43(57)48-34-29(20-46-49-44(62)47-28-16-11-10-12-17-28)38(54)31-32(39(34)55)37(53)26(6)41-33(31)42(56)45(8,61-41)59-19-18-30(58-9)23(3)40(60-27(7)50)25(5)36(52)24(4)35(21)51/h10-21,23-25,30,35-36,40,51-55H,1-9H3,(H,48,57)(H2,47,49,62)/b14-13+,19-18+,22-15-,46-20+/t21-,23+,24+,25+,30?,35-,36+,40+,45-/m0/s1
YGKKIZBIYBDCBF-HQTZQREOSA-N
Chemical. CAS: 51707-27-8. Formula: C45H54N4O12S. MW: 875. Semisynthetic. Ansamycin antibiotic. Hydrazone of 3-formylrifamycin SV. Selective inhibitor of bacterial DNA-dependent RNA polymerase (RNAP).
C45H54N4O12S
875
Vial
Ansamycin antibiotic. Hydrazone of 3-formylrifamycin SV. Selective inhibitor of bacterial DNA-dependent RNA polymerase (RNAP).
>90% (HPLC)
OC1=C(NC(/C(C)=CC=C[C@H](C)[C@H](O)[C@@H](C)[C@H]([C@H]2C)O)=O)C(/C=N/NC(NC3=CC=CC=C3)=S)=C(O)C4=C5C(O[C@@](O/C=C/[C@H](OC)[C@H]([C@H]2OC(C)=O)C)(C)C5=O)=C(C)C(O)=C41
Soluble in DMSO, aqueous acetonitrile or ethanol.
Semisynthetic.
Non-hazardous
Natural Products/Extracts
12352200
Stable for at least 2 years after receipt when stored at -20°C.