ProSci

UPRT Antibody

Product Code:
 
PSI-57-019
Product Group:
 
Primary Antibodies
Supplier:
 
ProSci
Host Type:
 
Rabbit
Antibody Isotype:
 
Rabbit Ig
Antibody Clonality:
 
Polyclonal
Regulatory Status:
 
RUO
Target Species:
 
Mouse
Applications:
  • Immunohistochemistry- Paraffin Embedded (IHC-P)
  • Western Blot (WB)
Storage:
 
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
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Western blot analysis in mouse liver tissue lysates (35ug/lane).
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UPRT Antibody immunohistochemistry analysis in formalin fixed and paraffin embedded human stomach tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.
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Western blot analysis in mouse liver tissue lysates (35ug/lane).
UPRT Antibody immunohistochemistry analysis in formalin fixed and paraffin embedded human stomach tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.

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PSI-57-019-400ul400ul£626.00
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Further Information

Additional Names:
Uracil phosphoribosyltransferase homolog, UPRT
Application Note:
For WB starting dilution is: 1:1000

For IHC-P starting dilution is: 1:10~50
Background:
This gene encodes uracil phosphoribosyltransferase, which catalyzes the conversion of uracil and 5-phosphoribosyl-1-R-diphosphate to uridine monophosphate (UMP). This reaction is an important part of nucleotide metabolism, specifically the pyrimidine salvage pathway. The enzyme localizes to the nucleus and cytoplasm. The protein is a potential target for rational design of drugs to treat parasitic infections and cancer.
Background References:
  • Zhao, F.J., et al. Prostate Cancer Prostatic Dis. 12(2):166-171(2009)
  • Li, J., et al. J. Hum. Genet. 52(5):415-422(2007)
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Homology:
Predicted species reactivity based on immunogen sequence: Bovine, Chicken, Monkey
Immunogen:
This UPRT antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 204-233 amino acids from the C-terminal region of human UPRT.
NCBI Gene ID #:
139596
NCBI Official Name:
Uracil phosphoribosyltransferase homolog
NCBI Official Symbol:
UPRT
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
34 kDa
Protein Accession #:
Q96BW1
Protein GI Number:
74751783
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Swissprot #:
Q96BW1
User NOte:
Optimal dilutions for each application to be determined by the researcher.