ProSci

SGCD Antibody

Product Code:
 
PSI-58-270
Product Group:
 
Primary Antibodies
Supplier:
 
ProSci
Host Type:
 
Rabbit
Antibody Isotype:
 
Rabbit Ig
Antibody Clonality:
 
Polyclonal
Regulatory Status:
 
RUO
Target Species:
 
Mouse
Application:
 
Western Blot (WB)
Storage:
 
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
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Western blot analysis in mouse liver tissue lysates (35ug/lane).
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Western blot analysis in mouse liver tissue lysates (35ug/lane).

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PSI-58-270-400ul400ul£626.00
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Further Information

Additional Names:
Delta-sarcoglycan, Delta-SG, 35 kDa dystrophin-associated glycoprotein, 35DAG, SGCD
Application Note:
For WB starting dilution is: 1:1000
Background:
The protein encoded by this gene is one of the four known components of the sarcoglycan complex, which is a subcomplex of the dystrophin-glycoprotein complex (DGC). DGC forms a link between the F-actin cytoskeleton and the extracellular matrix. This protein is expressed most abundantly in skeletal and cardiac muscle. Mutations in this gene have been associated with autosomal recessive limb-girdle muscular dystrophy and dilated cardiomyopathy. Alternatively spliced transcript variants encoding distinct isoforms have been observed for this gene.
Background References:
  • Bailey, S.D., et al. Diabetes Care 33(10):2250-2253(2010)
  • Rose, J.E., et al. Mol. Med. 16 (7-8), 247-253 (2010) :
  • Zimmerman, R.S., et al. Genet. Med. 12(5):268-278(2010)
  • Ordonez-Razo, R.M., et al. Genet Test Mol Biomarkers 14(2):237-240(2010)
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
This SGCD antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 232-261 amino acids from the C-terminal region of human SGCD.
NCBI Gene ID #:
6444
NCBI Official Name:
Delta-sarcoglycan
NCBI Official Symbol:
SGCD
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
32 kDa
Protein Accession #:
Q92629
Protein GI Number:
212276471
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Research Area:
Cell Cycle,Signal Transduction
Swissprot #:
Q92629
User NOte:
Optimal dilutions for each application to be determined by the researcher.