ProSci

Mouse Erbb2 Antibody

Product Code:
 
PSI-58-126
Product Group:
 
Primary Antibodies
Supplier:
 
ProSci
Host Type:
 
Rabbit
Antibody Isotype:
 
Rabbit Ig
Antibody Clonality:
 
Polyclonal
Regulatory Status:
 
RUO
Target Species:
 
Mouse
Application:
 
Western Blot (WB)
Storage:
 
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
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Western blot analysis in mouse testis tissue lysates (35ug/lane).
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Western blot analysis in mouse testis tissue lysates (35ug/lane).

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PSI-58-126-400ul400ul£626.00
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Further Information

Additional Names:
Receptor tyrosine-protein kinase erbB-2, Proto-oncogene Neu, Proto-oncogene c-ErbB-2, p185erbB2, CD340, Erbb2, Kiaa3023, Neu
Application Note:
For WB starting dilution is: 1:1000
Background:
Essential component of a neuregulin-receptor complex, although neuregulins do not interact with it alone. GP30 is a potential ligand for this receptor. Binds to the 5'-TCAAATTC-3' sequence in the MT-CO2 promoter and activates its transcription (By similarity).
Background References:
  • Cabodi, S., et al. FASEB J. 24(10):3796-3808(2010)
  • Johnson, E., et al. J. Biol. Chem. 285(38):29491-29501(2010)
  • Huck, L., et al. Proc. Natl. Acad. Sci. U.S.A. 107(35):15559-15564(2010)
  • Chuang, T.D., et al. J. Biol. Chem. 285(31):23598-23606(2010)
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
This Mouse Erbb2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 531-559 amino acids from the Central region of mouse Erbb2.
NCBI Gene ID #:
13866
NCBI Official Name:
Receptor tyrosine-protein kinase erbB-2
NCBI Official Symbol:
Erbb2
NCBI Organism:
Mus musculus
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
139 kDa
Protein Accession #:
P70424
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Research Area:
Cancer,Signal Transduction
Swissprot #:
P70424
User NOte:
Optimal dilutions for each application to be determined by the researcher.