ProSci

Tiparp Antibody

Product Code:
 
PSI-56-209
Product Group:
 
Primary Antibodies
Supplier:
 
ProSci
Host Type:
 
Rabbit
Antibody Isotype:
 
Rabbit Ig
Antibody Clonality:
 
Polyclonal
Regulatory Status:
 
RUO
Target Species:
  • Human
  • Mouse
Application:
 
Western Blot (WB)
Storage:
 
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
1 / 2
Western Blot at 1:500 dilution + mouse kidney lysate Lysates/proteins at 20 ug per lane.
2 / 2
Western blot analysis in MDA-MB231 cell line lysates (35ug/lane).
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Western Blot at 1:500 dilution + mouse kidney lysate Lysates/proteins at 20 ug per lane.
Western blot analysis in MDA-MB231 cell line lysates (35ug/lane).

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PSI-56-209-400ul400ul£626.00
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Further Information

Additional Names:
TCDD-inducible poly [ADP-ribose] polymerase, ADP-ribosyltransferase diphtheria toxin-like 14, ARTD14, Tiparp
Application Note:
For WB starting dilution is: 1:500
Background:
Tiparp is a poly [ADP-ribose] polymerase using NAD(+) as a substrate to transfer ADP-ribose onto glutamic acid residues of a protein acceptor; repeated rounds of ADP-ribosylation leads to the formation of poly(ADPribose) chains on the protein, thereby altering the function of the target protein. May play a role in the adaptative response to chemical exposure (TCDD) and thereby mediates certain effects of the chemicals.
Background References:
  • Schmahl, J., et al. Genes Dev. 22(23):3255-3267(2008)
  • Schmahl, J., et al. Nat. Genet. 39(1):52-60(2007)
  • Stryke, D., et al. Nucleic Acids Res. 31(1):278-281(2003)
  • Ma, Q. Arch. Biochem. Biophys. 404(2):309-316(2002)
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
This Tiparp antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 263-292 amino acids from the C-terminal region of human Tiparp.
NCBI Gene ID #:
99929
NCBI Official Name:
TCDD-inducible poly [ADP-ribose] polymerase
NCBI Official Symbol:
Tiparp
NCBI Organism:
Mus musculus
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
76 kDa
Protein Accession #:
Q8C1B2
Purification:
This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis
Swissprot #:
Q8C1B2
User NOte:
Optimal dilutions for each application to be determined by the researcher.