ProSci

DRD4 Antibody

Product Code:
 
PSI-63-631
Product Group:
 
Primary Antibodies
Supplier:
 
ProSci
Host Type:
 
Rabbit
Antibody Isotype:
 
Rabbit Ig
Antibody Clonality:
 
Polyclonal
Regulatory Status:
 
RUO
Target Species:
  • Human
  • Mouse
Applications:
  • Fluorescence-activated cell sorting (FACS)
  • Immunohistochemistry- Paraffin Embedded (IHC-P)
  • Western Blot (WB)
Storage:
 
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
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Western blot analysis of DRD4 Antibody in mouse heart tissue lysates (35ug/lane)
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Formalin-fixed and paraffin-embedded human brain tissue reacted with DRD4 Antibody , which was peroxidase-conjugated to the secondary antibody, followed by DAB staining.
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Western blot analysis of DRD4 Antibody in mouse heart tissue lysates (35ug/lane)
Formalin-fixed and paraffin-embedded human brain tissue reacted with DRD4 Antibody , which was peroxidase-conjugated to the secondary antibody, followed by DAB staining.

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PSI-63-631-400ul400ul£626.00
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Further Information

Additional Names:
D(4) dopamine receptor, D(2C) dopamine receptor, Dopamine D4 receptor, DRD4
Application Note:
For WB starting dilution is: 1:1000

For IHC-P starting dilution is: 1:10~50

For FACS starting dilution is: 1:10~50
Background:
DRD4 is the D4 subtype of the dopamine receptor. The D4 subtype is a G-protein coupled receptor which inhibits adenylyl cyclase. It is a target for drugs which treat schizophrenia and Parkinson disease.
Background References:
  • Livingstone,C.D., et.al., Biochem. J. 287 (PT 1), 277-282 (1992)
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
This DRD4 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 365-391 amino acids from the Central region of human DRD4.
NCBI Gene ID #:
1815
NCBI Official Name:
D(4) dopamine receptor
NCBI Official Symbol:
DRD4
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
48 kDa
Protein Accession #:
P21917
Protein GI Number:
1345939
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Research Area:
Neuroscience,Growth Factor
Swissprot #:
P21917
User NOte:
Optimal dilutions for each application to be determined by the researcher.