ProSci

IL1R1 Antibody

Product Code:
 
PSI-57-404
Product Group:
 
Primary Antibodies
Supplier:
 
ProSci
Host Type:
 
Rabbit
Antibody Isotype:
 
Rabbit Ig
Antibody Clonality:
 
Polyclonal
Regulatory Status:
 
RUO
Target Species:
  • Human
  • Mouse
Application:
 
Western Blot (WB)
Storage:
 
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
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Western blot analysis in HepG2 cell line lysates (35ug/lane).
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Western blot analysis in mouse liver tissue lysates (35ug/lane).
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Western blot analysis in HepG2 cell line lysates (35ug/lane).
Western blot analysis in mouse liver tissue lysates (35ug/lane).

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PSI-57-404-400ul400ul£626.00
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Further Information

Additional Names:
Interleukin-1 receptor type 1, IL-1R-1, IL-1RT-1, IL-1RT1, CD121 antigen-like family member A, Interleukin-1 receptor alpha, IL-1R-alpha, Interleukin-1 receptor type I, p80, CD121a, Interleukin-1 receptor type 1, membrane form, mIL-1R1, mIL-1RI, Interleukin-1 receptor type 1, soluble form, sIL-1R1, sIL-1RI, IL1R1, IL1R, IL1RA, IL1RT1
Application Note:
For WB starting dilution is: 1:1000
Background:
The protein encoded by this gene is a cytokine receptor that belongs to the interleukin 1 receptor family. This protein is a receptor for interleukin alpha (IL1A), interleukin beta (IL1B), and interleukin 1 receptor, type I(IL1R1/IL1RA). It is an important mediator involved in many cytokine induced immune and inflammatory responses. This gene along with interleukin 1 receptor, type II (IL1R2), interleukin 1 receptor-like 2 (IL1RL2), and interleukin 1 receptor-like 1 (IL1RL1) form a cytokine receptor gene cluster in a region mapped to chromosome 2q12.
Background References:
  • Fragoso, J.M., et al. Immunol. Lett. 133(2):106-111(2010)
  • Franchim, C.S., et al. Hypertens Pregnancy (2010) In press :
  • Melen, E., et al. J. Allergy Clin. Immunol. 126(3):631-637(2010)
  • de Wit, E., et al. Mamm. Genome (2010) In press :
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
This IL1R1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 422-450 amino acids from the C-terminal region of human IL1R1.
NCBI Gene ID #:
3554
NCBI Official Name:
Interleukin-1 receptor type 1
NCBI Official Symbol:
IL1R1
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
65 kDa
Protein Accession #:
P14778
Protein GI Number:
124308
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Research Area:
Immunology,Signal Transduction
Swissprot #:
P14778
User NOte:
Optimal dilutions for each application to be determined by the researcher.