ProSci

EID2 Antibody

Product Code:
 
PSI-61-993
Product Group:
 
Primary Antibodies
Supplier:
 
ProSci
Host Type:
 
Rabbit
Antibody Isotype:
 
Rabbit Ig
Antibody Clonality:
 
Polyclonal
Regulatory Status:
 
RUO
Target Species:
  • Human
  • Mouse
Application:
 
Western Blot (WB)
Storage:
 
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
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Western blot analysis in mouse spleen tissue lysates (15ug/lane).This demonstrates the detected EID2 protein (arrow).
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Western blot analysis in mouse spleen tissue lysates (15ug/lane).This demonstrates the detected EID2 protein (arrow).

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PSI-61-993-400ul400ul£626.00
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Further Information

Additional Names:
EP300-interacting inhibitor of differentiation 2, EID-2, CREBBP/EP300 inhibitor 2, EID-1-like inhibitor of differentiation 2, EID2 {ECO:0000312|EMBL:AAH301373}
Application Note:
For WB starting dilution is: 1:1000
Background:
EID2 interacts with EP300 and acts as a repressor of MYOD-dependent transcription and muscle differentiation. Inhibits EP300 histone acetyltransferase activity. Acts as a repressor of TGFB/SMAD transcriptional responses. It may act as a repressor of the TGFB/SMAD3-dependent signaling by selectively blocking formation of TGFB-induced SMAD3-SMAD4 complex.
Background References:
  • Lee, H.J., et al. J. Biol. Chem. 279(4):2666-2672(2004)
  • Ji, A., et al. Gene 318, 35-43 (2003) :
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
This EID2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 177-208 amino acids from the C-terminal region of human EID2.
NCBI Gene ID #:
163126
NCBI Official Name:
EP300-interacting inhibitor of differentiation 2
NCBI Official Symbol:
EID2
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
25 kDa
Protein Accession #:
Q8N6I1
Protein GI Number:
74762532
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Research Area:
Cell Cycle,Signal Transduction
Swissprot #:
Q8N6I1
User NOte:
Optimal dilutions for each application to be determined by the researcher.