ProSci

L2HGDH Antibody

Product Code:
 
PSI-55-109
Product Group:
 
Primary Antibodies
Supplier:
 
ProSci
Host Type:
 
Rabbit
Antibody Isotype:
 
Rabbit Ig
Antibody Clonality:
 
Polyclonal
Regulatory Status:
 
RUO
Target Species:
  • Human
  • Mouse
Application:
 
Western Blot (WB)
Storage:
 
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
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Western blot analysis in MDA-MB435 cell line and mouse kidney tissue lysates (35ug/lane).
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Western blot analysis in MDA-MB435 cell line and mouse kidney tissue lysates (35ug/lane).

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PSI-55-109-400ul400ul£626.00
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This product comes from: United States.
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Further Information

Additional Names:
L-2-hydroxyglutarate dehydrogenase, mitochondrial, Duranin, L2HGDH, C14orf160
Application Note:
For WB starting dilution is: 1:1000
Background:
This gene encodes L-2-hydroxyglutarate dehydrogenase, a FAD-dependent enzyme that oxidizes L-2-hydroxyglutarate to alpha-ketoglutarate in a variety of mammalian tissues. Mutations in this gene cause L-2-hydroxyglutaric aciduria, a rare autosomal recessive neurometabolic disorder resulting in moderate to severe mental retardation.
Background References:
  • Short, A.D., et al. Vet. Rec. 167(12):455-457(2010)
  • Steenweg, M.E., et al. Hum. Mutat. 31(4):380-390(2010)
  • Kranendijk, M., et al. Hum. Mutat. 31(3):279-283(2010)
  • Vilarinho, L., et al. J. Hum. Genet. 55(1):55-58(2010)
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
This L2HGDH antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 132-159 amino acids from the Central region of human L2HGDH.
NCBI Gene ID #:
79944
NCBI Official Name:
L-2-hydroxyglutarate dehydrogenase, mitochondrial
NCBI Official Symbol:
L2HGDH
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
50 kDa
Protein Accession #:
Q9H9P8
Protein GI Number:
317373422
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Research Area:
Cell Cycle,Obesity,Signal Transduction
Swissprot #:
Q9H9P8
User NOte:
Optimal dilutions for each application to be determined by the researcher.