ProSci

RAGE Antibody

Product Code:
 
PSI-61-373
Product Group:
 
Primary Antibodies
Supplier:
 
ProSci
Host Type:
 
Rabbit
Antibody Isotype:
 
Rabbit Ig
Antibody Clonality:
 
Polyclonal
Regulatory Status:
 
RUO
Target Species:
  • Human
  • Mouse
Applications:
  • Immunohistochemistry- Paraffin Embedded (IHC-P)
  • Western Blot (WB)
Storage:
 
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
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Western blot analysis of AGER-K44 in mouse lung tissue lysates (35ug/lane)
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Formalin-fixed and paraffin-embedded human cancer tissue reacted with the primary antibody, which was peroxidase-conjugated to the secondary antibody, followed by AEC staining. BC = breast carcinoma; HC = hepatocarcinoma.
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Western blot analysis of AGER-K44 in mouse lung tissue lysates (35ug/lane)
Formalin-fixed and paraffin-embedded human cancer tissue reacted with the primary antibody, which was peroxidase-conjugated to the secondary antibody, followed by AEC staining. BC = breast carcinoma; HC = hepatocarcinoma.

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PSI-61-373-400ul400ul£626.00
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Further Information

Additional Names:
Advanced glycosylation end product-specific receptor, Receptor for advanced glycosylation end products, AGER, RAGE
Application Note:
For WB starting dilution is: 1:1000

For IHC-P starting dilution is: 1:50~100
Background:
AGER is a member of the immunoglobulin superfamily of cell surface molecules. It is a receptor for various molecules, including the amyloidogenic form of serum amyloid A, amyloid-beta protein, members of the S100/calgranulin superfamily and advanced glycation end products.
Background References:
  • Schlueter, C., et al., Biochim. Biophys. Acta 1630(1):1-6 (2003). Shanmugam, N., et al., J. Biol. Chem. 278(37):34834-34844 (2003). Kuniyasu, H., et al., Oncol. Rep. 10(2):445-448 (2003). Hsieh, H.L., et al., Biochem. Biophys. Res. Commun. 307(2):375-381 (2003). Rocken, C., et al., Am. J. Pathol. 162(4):1213-1220 (2003).
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
This RAGE (AGER) antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 29-59 amino acids from the N-terminal region of human RAGE (AGER).
NCBI Gene ID #:
177
NCBI Official Name:
Advanced glycosylation end product-specific receptor
NCBI Official Symbol:
AGER
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
43 kDa
Protein Accession #:
Q15109
Protein GI Number:
2497317
Purification:
This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis
Research Area:
Cell Cycle,Neuroscience
Swissprot #:
Q15109
User NOte:
Optimal dilutions for each application to be determined by the researcher.