Antibody Isotype:
Rabbit Ig
Antibody Clonality:
Polyclonal
Application:
Western Blot (WB)
Storage:
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
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This product comes from:
United States.
Typical lead time:
14-21 working days.
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- Further Information
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Further Information
Myosin-7, Myosin heavy chain 7, Myosin heavy chain slow isoform, MyHC-slow, Myosin heavy chain, cardiac muscle beta isoform, MyHC-beta, MYH7, MYHCB
For WB starting dilution is: 1:1000
Muscle myosin is a hexameric protein containing 2 heavy
chain subunits, 2 alkali light chain subunits, and 2 regulatory
light chain subunits. This gene encodes the beta (or slow) heavy
chain subunit of cardiac myosin. It is expressed predominantly in
normal human ventricle. It is also expressed in skeletal muscle
tissues rich in slow-twitch type I muscle fibers. Changes in the
relative abundance of this protein and the alpha (or fast) heavy
subunit of cardiac myosin correlate with the contractile velocity
of cardiac muscle. Its expression is also altered during thyroid
hormone depletion and hemodynamic overloading. Mutations in this
gene are associated with familial hypertrophic cardiomyopathy,
myosin storage myopathy, dilated cardiomyopathy, and Laing
early-onset distal myopathy.
- Millat, G., et al. Clin. Chim. Acta 411 (23-24), 1983-1991 (2010) :
- Eijgelsheim, M., et al. Hum. Mol. Genet. 19(19):3885-3894(2010)
- Millat, G., et al. EurMed Genet 53(5):261-267(2010)
- Muelas, N., et al. Neurology 75(8):732-741(2010)
Supplied in PBS with 0.09% (W/V) sodium azide.
batch dependent
Unconjugated
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
This MYH7 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 185-211 amino acids from the N-terminal region of human MYH7.
4625
Myosin-7
MYH7
Homo sapiens
Liquid
PREDICTED MOLECULAR WEIGHT:
223 kDa
P12883
83304912
This antibody is purified through a protein A column, followed by peptide affinity purification.
Cell Cycle,Immunology,Signal Transduction
P12883
Optimal dilutions for each application to be determined by the researcher.