ProSci

ACE Antibody

Product Code:
 
PSI-63-208
Product Group:
 
Primary Antibodies
Supplier:
 
ProSci
Host Type:
 
Rabbit
Antibody Isotype:
 
Rabbit Ig
Antibody Clonality:
 
Polyclonal
Regulatory Status:
 
RUO
Target Species:
  • Human
  • Mouse
Application:
 
Western Blot (WB)
Storage:
 
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
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Western blot analysis of anti-ACE Antibody in mouse lung tissue lysates (35ug/lane)
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Western blot analysis of anti-ACE Antibody in mouse lung tissue lysates (35ug/lane)

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PSI-63-208-400ul400ul£626.00
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This product comes from: United States.
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Further Information

Additional Names:
Angiotensin-converting enzyme, ACE, 321-, Dipeptidyl carboxypeptidase I, Kininase II, CD143, Angiotensin-converting enzyme, soluble form, ACE, DCP, DCP1
Application Note:
For WB starting dilution is: 1:1000
Background:
ACE is an enzyme involved in catalyzing the conversion of angiotensin I into a physiologically active peptide angiotensin II. Angiotensin II is a potent vasopressor and aldosterone-stimulating peptide that controls blood pressure and fluid-electrolyte balance. This enzyme plays a key role in the renin-angiotensin system. Many studies have associated the presence or absence of a 287 bp Alu repeat element in this gene with the levels of circulating enzyme or cardiovascular pathophysiologies. Two most abundant alternatively spliced variants of this gene encode two isozymes - the somatic form and the testicular form that are equally active.
Background References:
  • du Cheyron,D.,Crit. Care Med. 36 (12), 3178-3183 (2008)
  • Pang,S., Biochem. J. 358 (PT 1), 185-192 (2001)
  • Woodman,Z.L., Biochem. J. 347 PT 3, 711-718 (2000)
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
This ACE antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1274-1306 amino acids from the C-terminal region of human ACE.
NCBI Gene ID #:
1636
NCBI Official Name:
Angiotensin-converting enzyme
NCBI Official Symbol:
ACE
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
150 kDa
Protein Accession #:
P12821
Protein GI Number:
113045
Purification:
This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis
Research Area:
Cancer,Cell Cycle,Obesity,Signal Transduction
Swissprot #:
P12821
User NOte:
Optimal dilutions for each application to be determined by the researcher.