ProSci

PDGFRL Antibody

Product Code:
 
PSI-59-183
Product Group:
 
Primary Antibodies
Supplier:
 
ProSci
Host Type:
 
Rabbit
Antibody Isotype:
 
Rabbit Ig
Antibody Clonality:
 
Polyclonal
Regulatory Status:
 
RUO
Target Species:
  • Human
  • Mouse
Application:
 
Western Blot (WB)
Storage:
 
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
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Western blot analysis in mouse heart tissue lysates (35ug/lane).
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Western blot analysis in mouse heart tissue lysates (35ug/lane).

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PSI-59-183-400ul400ul£626.00
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Further Information

Additional Names:
Platelet-derived growth factor receptor-like protein, PDGFR-like protein, PDGF receptor beta-like tumor suppressor, PDGFRL, PRLTS
Application Note:
For WB starting dilution is: 1:1000
Background:
This gene encodes a protein with significant sequence similarity to the ligand binding domain of platelet-derived growth factor receptor beta. Mutations in this gene, or deletion of a chromosomal segment containing this gene, are associated with sporadic hepatocellular carcinomas, colorectal cancers, and non-small cell lung cancers. This suggests this gene product may function as a tumor suppressor.
Background References:
  • Davila, S., et al. Genes Immun. 11(3):232-238(2010)
  • Guo, F.J., et al. World J. Gastroenterol. 16(12):1465-1472(2010)
  • Riker, A.I., et al. BMC Med Genomics 1, 13 (2008) :
  • Xu, M., et al. BMC GenomicsSUPPL 1, S12 (2008) :
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Homology:
Predicted species reactivity based on immunogen sequence: Bovine, Monkey
Immunogen:
This PDGFRL antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 16-44 amino acids from the N-terminal region of human PDGFRL.
NCBI Gene ID #:
5157
NCBI Official Name:
Platelet-derived growth factor receptor-like protein
NCBI Official Symbol:
PDGFRL
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
42 kDa
Protein Accession #:
Q15198
Protein GI Number:
74762141
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Research Area:
Cancer
Swissprot #:
Q15198
User NOte:
Optimal dilutions for each application to be determined by the researcher.