ProSci

SMARCB1 Antibody

Product Code:
 
PSI-57-668
Product Group:
 
Primary Antibodies
Supplier:
 
ProSci
Host Type:
 
Rabbit
Antibody Isotype:
 
Rabbit Ig
Antibody Clonality:
 
Polyclonal
Regulatory Status:
 
RUO
Target Species:
  • Human
  • Mouse
Application:
 
Western Blot (WB)
Storage:
 
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
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Western blot analysis in human placenta tissue lysates (35ug/lane).
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Western blot analysis in mouse brain tissue lysates (35ug/lane).
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Western blot analysis in human placenta tissue lysates (35ug/lane).
Western blot analysis in mouse brain tissue lysates (35ug/lane).

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PSI-57-668-400ul400ul£626.00
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Further Information

Additional Names:
SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily B member 1, BRG1-associated factor 47, BAF47, Integrase interactor 1 protein, SNF5 homolog, hSNF5, SMARCB1, BAF47, INI1, SNF5L1
Application Note:
For WB starting dilution is: 1:1000
Background:
The protein encoded by this gene is part of a complex that relieves repressive chromatin structures, allowing the transcriptional machinery to access its targets more effectively. The encoded nuclear protein may also bind to and enhance the DNA joining activity of HIV-1 integrase. This gene has been found to be a tumor suppressor, and mutations in it have been associated with malignant rhabdoid tumors. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq].
Background References:
  • Bakshi, R., et al. J. Cell. Physiol. 225(2):569-576(2010)
  • Bailey, S.D., et al. Diabetes Care 33(10):2250-2253(2010)
  • Hadfield, K.D., et al. J. Med. Genet. 47(8):567-568(2010)
  • Kohashi, K., et al. Mod. Pathol. 23(7):981-990(2010)
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
This SMARCB1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 52-81 amino acids from the N-terminal region of human SMARCB1.
NCBI Gene ID #:
6598
NCBI Official Name:
SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily B member 1
NCBI Official Symbol:
SMARCB1
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
44 kDa
Protein Accession #:
Q12824
Protein GI Number:
51338799
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Research Area:
Cancer
Swissprot #:
Q12824
User NOte:
Optimal dilutions for each application to be determined by the researcher.