Further Information
Eukaryotic translation initiation factor 3 subunit H {ECO:0000255|HAMAP-Rule:MF_03007}, eIF3h {ECO:0000255|HAMAP-Rule:MF_03007}, Eukaryotic translation initiation factor 3 subunit 3 {ECO:0000255|HAMAP-Rule:MF_03007}, eIF-3-gamma, eIF3 p40 subunit {ECO:0000255|HAMAP-Rule:MF_03007}, EIF3H {ECO:0000255|HAMAP-Rule:MF_03007}
For WB starting dilution is: 1:1000
For IHC-P starting dilution is: 1:10~50
Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is required for several steps in the initiation of protein synthesis. The eIF-3 complex associates with the 40S ribosome and facilitates the recruitment of eIF-1, eIF-1A, eIF-2:GTP:methionyl-tRNAi and eIF-5 to form the 43S preinitiation complex (43S PIC). The eIF-3 complex stimulates mRNA recruitment to the 43S PIC and scanning of the mRNA for AUG recognition. The eIF-3 complex is also required for disassembly and recycling of posttermination ribosomal complexes and subsequently prevents premature joining of the 40S and 60S ribosomal subunits prior to initiation.
- Kupfer, S.S., et al. Gastroenterology 139(5):1677-1685(2010)
- Hawken, S.J., et al. Hum. Genet. 128(1):89-101(2010)
- Cappuzzo, F., et al.Thorac Oncol 4(4):472-478(2009)
- Venkatesan, K., et al. Nat. Methods 6(1):83-90(2009)
Supplied in PBS with 0.09% (W/V) sodium azide.
batch dependent
Unconjugated
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Predicted species reactivity based on immunogen sequence: Zebrafish, Bovine, Chicken, Mouse, Rat
This EIF3H antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 70-99 amino acids from the N-terminal region of human EIF3H.
8667
Eukaryotic translation initiation factor 3 subunit H {ECO:0000255|HAMAP-Rule:MF_03007}
EIF3H
Homo sapiens
Liquid
PREDICTED MOLECULAR WEIGHT:
40 kDa
O15372
This antibody is purified through a protein A column, followed by peptide affinity purification.
O15372
Optimal dilutions for each application to be determined by the researcher.