ProSci

CATSPER2 Antibody

Product Code:
 
PSI-60-254
Product Group:
 
Primary Antibodies
Supplier:
 
ProSci
Host Type:
 
Rabbit
Antibody Isotype:
 
Rabbit Ig
Antibody Clonality:
 
Polyclonal
Regulatory Status:
 
RUO
Target Species:
 
Human
Application:
 
Western Blot (WB)
Storage:
 
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
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Western blot analysis in MDA-MB453 cell line lysates (35ug/lane).
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Western blot analysis in MDA-MB453 cell line lysates (35ug/lane).

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PSI-60-254-400ul400ul£626.00
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Further Information

Additional Names:
Cation channel sperm-associated protein 2, CatSper2, CATSPER2
Application Note:
For WB starting dilution is: 1:1000
Background:
Calcium ions play a primary role in the regulation of sperm motility. This gene belongs to a family of putative cation channels that are specific to spermatozoa and localize to the flagellum. The protein family features a single repeat with six membrane-spanning segments and a predicted calcium-selective pore region. This gene is part of a tandem repeat on chromosome 15q15; the second copy of this gene is thought to be a pseudogene. Additional splice variants have been described but their full-length nature has not been determined.
Background References:
  • Rose, J.E., et al. Mol. Med. 16 (7-8), 247-253 (2010) :
  • Lamesch, P., et al. Genomics 89(3):307-315(2007)
  • Zhang, D., et al. J. Biol. Chem. 281(31):22332-22341(2006)
  • Clapham, D.E., et al. Pharmacol. Rev. 57(4):451-454(2005)
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
This CATSPER2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 472-500 amino acids from the C-terminal region of human CATSPER2.
NCBI Gene ID #:
117155
NCBI Official Name:
Cation channel sperm-associated protein 2
NCBI Official Symbol:
CATSPER2
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
62 kDa
Protein Accession #:
Q96P56
Protein GI Number:
156631018
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Swissprot #:
Q96P56
User NOte:
Optimal dilutions for each application to be determined by the researcher.