Further Information
E3 ubiquitin-protein ligase FANCL, 632-, Fanconi anemia group L protein, Fanconi anemia-associated polypeptide of 43 kDa, FAAP43, FANCL, PHF9
For WB starting dilution is: 1:1000
The Fanconi anemia complementation group (FANC) currently
includes FANCA, FANCB, FANCC, FANCD1 (also called BRCA2), FANCD2,
FANCE, FANCF, FANCG, FANCI, FANCJ (also called BRIP1), FANCL, FANCM
and FANCN (also called PALB2). The previously defined group FANCH
is the same as FANCA. Fanconi anemia is a genetically heterogeneous
recessive disorder characterized by cytogenetic instability,
hypersensitivity to DNA crosslinking agents, increased chromosomal
breakage, and defective DNA repair. The members of the Fanconi
anemia complementation group do not share sequence similarity; they
are related by their assembly into a common nuclear protein
complex. This gene encodes the protein for complementation group L.
Alternative splicing results in two transcript variants encoding
different isoforms.
- Zhang, J., et al. J. Clin. Invest. 120(5):1524-1534(2010)
- Garcia, M.J., et al. Carcinogenesis 30(11):1898-1902(2009)
- McWilliams, R.R., et al. Cancer Epidemiol. Biomarkers Prev. 18(9):2549-2552(2009)
- Longerich, S., et al. J. Biol. Chem. 284(35):23182-23186(2009)
Supplied in PBS with 0.09% (W/V) sodium azide.
batch dependent
Unconjugated
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
This FANCL antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 274-302 amino acids from the C-terminal region of human FANCL.
55120
E3 ubiquitin-protein ligase FANCL
FANCL
Homo sapiens
Liquid
PREDICTED MOLECULAR WEIGHT:
43 kDa
Q9NW38
116241360
This antibody is purified through a protein A column, followed by peptide affinity purification.
Q9NW38
Optimal dilutions for each application to be determined by the researcher.