ProSci

SNAPC1 Antibody

Product Code:
 
PSI-58-484
Product Group:
 
Primary Antibodies
Supplier:
 
ProSci
Host Type:
 
Rabbit
Antibody Isotype:
 
Rabbit Ig
Antibody Clonality:
 
Polyclonal
Regulatory Status:
 
RUO
Target Species:
 
Human
Application:
 
Western Blot (WB)
Storage:
 
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
1 / 2
Western blot analysis in Jurkat cell line lysates (35ug/lane).
2 / 2
Western blot analysis of SNAPC1 using rabbit polyclonal SNAPC1 Antibody using 293 cell lysates (2 ug/lane) either nontransfected (Lane 1) or transiently transfected (Lane 2) with the SNAPC1 gene.
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Western blot analysis in Jurkat cell line lysates (35ug/lane).
Western blot analysis of SNAPC1 using rabbit polyclonal SNAPC1 Antibody using 293 cell lysates (2 ug/lane) either nontransfected (Lane 1) or transiently transfected (Lane 2) with the SNAPC1 gene.

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PSI-58-484-400ul400ul£626.00
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Further Information

Additional Names:
snRNA-activating protein complex subunit 1, SNAPc subunit 1, Proximal sequence element-binding transcription factor subunit gamma, PSE-binding factor subunit gamma, PTF subunit gamma, Small nuclear RNA-activating complex polypeptide 1, snRNA-activating protein complex 43 kDa subunit, SNAPc 43 kDa subunit, SNAPC1, SNAP43
Application Note:
For WB starting dilution is: 1:1000
Background:
Part of the SNAPc complex required for the transcription of both RNA polymerase II and III small-nuclear RNA genes. Binds to the proximal sequence element (PSE), a non-TATA-box basal promoter element common to these 2 types of genes. Recruits TBP and BRF2 to the U6 snRNA TATA box.
Background References:
  • Gu, L., et al. J. Biol. Chem. 280(30):27697-27704(2005)
  • Hinkley, C.S., et al. J. Biol. Chem. 278(20):18649-18657(2003)
  • Ma, B., et al. J. Biol. Chem. 276(7):5027-5035(2001)
  • Hirsch, H.A., et al. Mol. Cell. Biol. 20(24):9182-9191(2000)
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Homology:
Predicted species reactivity based on immunogen sequence: Monkey
Immunogen:
This SNAPC1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 139-168 amino acids from the Central region of human SNAPC1.
NCBI Gene ID #:
6617
NCBI Official Name:
snRNA-activating protein complex subunit 1
NCBI Official Symbol:
SNAPC1
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
43 kDa
Protein Accession #:
Q16533
Protein GI Number:
8134716
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Swissprot #:
Q16533
User NOte:
Optimal dilutions for each application to be determined by the researcher.