Further Information
Transcription initiation factor TFIID subunit 6, RNA polymerase II TBP-associated factor subunit E, Transcription initiation factor TFIID 70 kDa subunit, TAF(II)70, TAFII-70, TAFII70, Transcription initiation factor TFIID 80 kDa subunit, TAF(II)80, TAFII-80, TAFII80, TAF6, TAF2E, TAFII70
For WB starting dilution is: 1:1000
Initiation of transcription by RNA polymerase II requires
the activities of more than 70 polypeptides. The protein that
coordinates these activities is transcription factor IID (TFIID),
which binds to the core promoter to position the polymerase
properly, serves as the scaffold for assembly of the remainder of
the transcription complex, and acts as a channel for regulatory
signals. TFIID is composed of the TATA-binding protein (TBP) and a
group of evolutionarily conserved proteins known as TBP-associated
factors or TAFs. TAFs may participate in basal transcription, serve
as coactivators, function in promoter recognition or modify general
transcription factors (GTFs) to facilitate complex assembly and
transcription initiation. This gene encodes one of the smaller
subunits of TFIID that binds weakly to TBP but strongly to TAF1,
the largest subunit of TFIID. Alternative splicing results in
multiple transcript variants.
- Theisen, J.W., et al. Mol. Cell. Biol. (2010) In press :
- Wilhelm, E., et al. BMC Mol. Biol. 11, 10 (2010) :
- Wilhelm, E., et al. PLoS ONE(7), E2721 (2008) :
- Frontini, M., et al. Mol. Cell. Biol. 25(11):4638-4649(2005)
Supplied in PBS with 0.09% (W/V) sodium azide.
batch dependent
Unconjugated
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Predicted species reactivity based on immunogen sequence: Mouse, Rat
This TAF6 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 24-53 amino acids from the N-terminal region of human TAF6.
6878
Transcription initiation factor TFIID subunit 6
TAF6
Homo sapiens
Liquid
PREDICTED MOLECULAR WEIGHT:
73 kDa
P49848
1729810
This antibody is purified through a protein A column, followed by peptide affinity purification.
P49848
Optimal dilutions for each application to be determined by the researcher.