ProSci

TAF1A Antibody

Product Code:
 
PSI-58-292
Product Group:
 
Primary Antibodies
Supplier:
 
ProSci
Host Type:
 
Rabbit
Antibody Isotype:
 
Rabbit Ig
Antibody Clonality:
 
Polyclonal
Regulatory Status:
 
RUO
Target Species:
 
Human
Application:
 
Western Blot (WB)
Storage:
 
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
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Western blot analysis in Y79 cell line lysates (35ug/lane).
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Western blot analysis in Y79 cell line lysates (35ug/lane).

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PSI-58-292-400ul400ul£626.00
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Further Information

Additional Names:
TATA box-binding protein-associated factor RNA polymerase I subunit A, RNA polymerase I-specific TBP-associated factor 48 kDa, TAFI48, TATA box-binding protein-associated factor 1A, TBP-associated factor 1A, Transcription factor SL1, Transcription initiation factor SL1/TIF-IB subunit A, TAF1A
Application Note:
For WB starting dilution is: 1:1000
Background:
Initiation of transcription by RNA polymerase I requires the formation of a complex composed of the TATA-binding protein (TBP) and three TBP-associated factors (TAFs) specific for RNA polymerase I. This complex, known as SL1, binds to the core promoter of ribosomal RNA genes to position the polymerase properly and acts as a channel for regulatory signals. This gene encodes the smallest SL1-specific TAF. Two transcripts encoding different isoforms have been identified.
Background References:
  • Greco-Stewart, V.S., et al. Virology 386(1):12-15(2009)
  • Yamamoto, K., et al. Mol. Cell. Biol. 24(14):6338-6349(2004)
  • Dynes, J.L., et al. J. Biochem. 135(3):429-438(2004)
  • Hirschler-Laszkiewicz, I., et al. J. Biol. Chem. 278(21):18953-18959(2003)
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
This TAF1A antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 68-97 amino acids from the N-terminal region of human TAF1A.
NCBI Gene ID #:
9015
NCBI Official Name:
TATA box-binding protein-associated factor RNA polymerase I subunit A
NCBI Official Symbol:
TAF1A
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
53 kDa
Protein Accession #:
Q15573
Protein GI Number:
74739864
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Swissprot #:
Q15573
User NOte:
Optimal dilutions for each application to be determined by the researcher.