Antibody Isotype:
Rabbit Ig
Antibody Clonality:
Polyclonal
Applications:- Immunohistochemistry- Paraffin Embedded (IHC-P)
- Western Blot (WB)
Storage:
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
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This product comes from:
United States.
Typical lead time:
14-21 working days.
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Further Information
Dual specificity protein phosphatase 9, Mitogen-activated protein kinase phosphatase 4, MAP kinase phosphatase 4, MKP-4, DUSP9, MKP4
For WB starting dilution is: 1:1000
For IHC-P starting dilution is: 1:10~50
The protein encoded by this gene is a member of the dual
specificity protein phosphatase subfamily. These phosphatases
inactivate their target kinases by dephosphorylating both the
phosphoserine/threonine and phosphotyrosine residues. They
negatively regulate members of the mitogen-activated protein (MAP)
kinase superfamily (MAPK/ERK, SAPK/JNK, p38), which is associated
with cellular proliferation and differentiation. Different members
of the family of dual specificity phosphatases show distinct
substrate specificities for various MAP kinases, different tissue
distribution and subcellular localization, and different modes of
inducibility of their expression by extracellular stimuli. This
gene product shows selectivity for members of the ERK family of MAP
kinases, is expressed only in placenta, kidney, and fetal liver,
and is localized to the cytoplasm and nucleus. [provided by
RefSeq].
- Voight, B.F., et al. Nat. Genet. 42(7):579-589(2010)
- Liu, Y., et al. Cancer Res. 67(22):10711-10719(2007)
- Ross, M.T., et al. Nature 434(7031):325-337(2005)
- Muda, M., et al. J. Biol. Chem. 272(8):5141-5151(1997)
Supplied in PBS with 0.09% (W/V) sodium azide.
batch dependent
Unconjugated
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
This DUSP9 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 300-329 amino acids from the C-terminal region of human DUSP9.
1852
Dual specificity protein phosphatase 9
DUSP9
Homo sapiens
Liquid
PREDICTED MOLECULAR WEIGHT:
42 kDa
Q99956
3913541
This antibody is purified through a protein A column, followed by peptide affinity purification.
Signal Transduction
Q99956
Optimal dilutions for each application to be determined by the researcher.