Further Information
Growth/differentiation factor 5, GDF-5, Bone morphogenetic protein 14, BMP-14, Cartilage-derived morphogenetic protein 1, CDMP-1, Lipopolysaccharide-associated protein 4, LAP-4, LPS-associated protein 4, Radotermin, GDF5, BMP14, CDMP1
For WB starting dilution is: 1:1000
For IHC-P starting dilution is: 1:10~50
The protein encoded by this gene is a member of the bone
morphogenetic protein (BMP) family and the TGF-beta superfamily.
This group of proteins is characterized by a polybasic proteolytic
processing site which is cleaved to produce a mature protein
containing seven conserved cysteine residues. The members of this
family are regulators of cell growth and differentiation in both
embryonic and adult tissues. Mutations in this gene are associated
with acromesomelic dysplasia, Hunter-Thompson type; brachydactyly,
type C; and chondrodysplasia, Grebe type. These associations
confirm that the gene product plays a role in skeletal development.
- Posthumus, M., et al. Rheumatology (Oxford) 49(11):2090-2097(2010)
- Rouault, K., et al. Osteoarthr. Cartil. 18(9):1144-1149(2010)
- Zintzaras, E., et al. Am. J. Epidemiol. 171(8):851-858(2010)
- Davila, S., et al. Genes Immun. 11(3):232-238(2010)
Supplied in PBS with 0.09% (W/V) sodium azide.
batch dependent
Unconjugated
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Predicted species reactivity based on immunogen sequence: Mouse
This GDF5 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 343-371 amino acids from the C-terminal region of human GDF5.
8200
Growth/differentiation factor 5
GDF5
Homo sapiens
Liquid
PREDICTED MOLECULAR WEIGHT:
55 kDa
P43026
20141384
This antibody is purified through a protein A column, followed by peptide affinity purification.
Signal Transduction
P43026
Optimal dilutions for each application to be determined by the researcher.