ProSci

DAAM2 Antibody

Product Code:
 
PSI-63-022
Product Group:
 
Primary Antibodies
Supplier:
 
ProSci
Host Type:
 
Rabbit
Antibody Isotype:
 
Rabbit Ig
Antibody Clonality:
 
Polyclonal
Regulatory Status:
 
RUO
Target Species:
 
Human
Applications:
  • Immunohistochemistry- Paraffin Embedded (IHC-P)
  • Western Blot (WB)
Storage:
 
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
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Western blot analysis of DAAM2 (Human N-term) in 293 cell line lysates (35ug/lane)
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Formalin-fixed and paraffin-embedded human brain tissue reacted with DAAM2 Antibody , which was peroxidase-conjugated to the secondary antibody, followed by DAB staining.
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Western blot analysis of DAAM2 (Human N-term) in 293 cell line lysates (35ug/lane)
Formalin-fixed and paraffin-embedded human brain tissue reacted with DAAM2 Antibody , which was peroxidase-conjugated to the secondary antibody, followed by DAB staining.

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PSI-63-022-400ul400ul£626.00
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Further Information

Additional Names:
Disheveled-associated activator of morphogenesis 2, DAAM2, KIAA0381
Application Note:
For WB starting dilution is: 1:1000

For IHC-P starting dilution is: 1:10~50
Background:
DAAM2 is a 1068 amino acis protein belonging to the formin homology family. It contains one of each DAD (diaphanous autoregulatory), FH1 (formin homology 1), FH2 (formin homology 2) and GBD/FH3 (Rho GTPase-binding/formin homology 3) domain. Its main function is actin cytoskeleton organization, thus leading to cell organization and biogenesis. It plays a role in Rho GTPase binding and is expressed mostly in spinal cord and nerve tissues.
Background References:
  • Katoh,M., Int. J. Oncol. 22 (4), 915-920 (2003)
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
This DAAM2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 68-97 amino acids from the N-terminal region of human DAAM2.
NCBI Gene ID #:
23500
NCBI Official Name:
Disheveled-associated activator of morphogenesis 2
NCBI Official Symbol:
DAAM2
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
123 kDa
Protein Accession #:
Q86T65
Protein GI Number:
62906888
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Research Area:
Signal Transduction
Swissprot #:
Q86T65
User NOte:
Optimal dilutions for each application to be determined by the researcher.