ProSci

PRKRIR Antibody

Product Code:
 
PSI-58-044
Product Group:
 
Primary Antibodies
Supplier:
 
ProSci
Host Type:
 
Rabbit
Antibody Isotype:
 
Rabbit Ig
Antibody Clonality:
 
Polyclonal
Regulatory Status:
 
RUO
Target Species:
 
Human
Application:
 
Western Blot (WB)
Storage:
 
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
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Western blot analysis in MCF-7 cell line lysates (35ug/lane).
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Western blot analysis in MCF-7 cell line lysates (35ug/lane).

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PSI-58-044-400ul400ul£626.00
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Further Information

Additional Names:
52 kDa repressor of the inhibitor of the protein kinase, p52rIPK, 58 kDa interferon-induced protein kinase-interacting protein, p58IPK-interacting protein, Death-associated protein 4, THAP domain-containing protein 0, PRKRIR, DAP4, P52RIPK, THAP0
Application Note:
For WB starting dilution is: 1:1000
Background:
Upstream regulator of interferon-induced serine/threonine protein kinase R (PKR). May block the PKR-inhibitory function of P58IPK, resulting in restoration of kinase activity and suppression of cell growth.
Background References:
  • Silva, L.K., et al. Eur. J. Hum. Genet. 18(11):1221-1227(2010)
  • Johnatty, S.E., et al. PLoS Genet.(7), E1001016 (2010) :
  • Lee, J.H., et al. KoreanGastroenterol 42(6):484-495(2003)
  • Lin, Y., et al. J. Biol. Chem. 277(50):47991-48001(2002)
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
This PRKRIR antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 102-130 amino acids from the N-terminal region of human PRKRIR.
NCBI Gene ID #:
5612
NCBI Official Name:
52 kDa repressor of the inhibitor of the protein kinase
NCBI Official Symbol:
PRKRIR
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
88 kDa
Protein Accession #:
O43422
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Research Area:
Signal Transduction
Swissprot #:
O43422
User NOte:
Optimal dilutions for each application to be determined by the researcher.