ProSci

FGD3 Antibody

Product Code:
 
PSI-60-372
Product Group:
 
Primary Antibodies
Supplier:
 
ProSci
Host Type:
 
Rabbit
Antibody Isotype:
 
Rabbit Ig
Antibody Clonality:
 
Polyclonal
Regulatory Status:
 
RUO
Target Species:
 
Human
Application:
 
Western Blot (WB)
Storage:
 
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
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Western blot analysis in A549 cell line lysates (35ug/lane).
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Western blot analysis in A549 cell line lysates (35ug/lane).

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PSI-60-372-400ul400ul£626.00
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Further Information

Additional Names:
FYVE, RhoGEF and PH domain-containing protein 3, Zinc finger FYVE domain-containing protein 5, FGD3, ZFYVE5
Application Note:
For WB starting dilution is: 1:1000
Background:
FGD3 promotes the formation of filopodia. May activate CDC42, a member of the Ras-like family of Rho-and Rac proteins, by exchanging bound GDP for free GTP. Plays a role in regulating the actin cytoskeleton and cell shape (By similarity).
Background References:
  • Rose, J.E., et al. Mol. Med. 16 (7-8), 247-253 (2010) :
  • Delague, V., et al. Am. J. Hum. Genet. 81(1):1-16(2007)
  • Humphray, S.J., et al. Nature 429(6990):369-374(2004)
  • Rabizadeh, S., et al. Cytokine Growth Factor Rev. 14 (3-4), 225-239 (2003) :
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
This FGD3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 575-601 amino acids from the C-terminal region of human FGD3.
NCBI Gene ID #:
89846
NCBI Official Name:
FYVE, RhoGEF and PH domain-containing protein 3
NCBI Official Symbol:
FGD3
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
79 kDa
Protein Accession #:
Q5JSP0
Protein GI Number:
61213216
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Research Area:
Signal Transduction
Swissprot #:
Q5JSP0
User NOte:
Optimal dilutions for each application to be determined by the researcher.