ProSci

SPIRE1 Antibody

Product Code:
 
PSI-59-219
Product Group:
 
Primary Antibodies
Supplier:
 
ProSci
Host Type:
 
Rabbit
Antibody Isotype:
 
Rabbit Ig
Antibody Clonality:
 
Polyclonal
Regulatory Status:
 
RUO
Target Species:
 
Human
Application:
 
Western Blot (WB)
Storage:
 
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
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Western blot analysis in 293 cell line lysates (35ug/lane).
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Western blot analysis in 293 cell line lysates (35ug/lane).

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PSI-59-219-400ul400ul£626.00
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Further Information

Additional Names:
Protein spire homolog 1, Spir-1, SPIRE1 {ECO:0000312|EMBL:AAI252071}, KIAA1135, SPIR1
Application Note:
For WB starting dilution is: 1:1000
Background:
Spire proteins, such as SPIRE1, are highly conserved between species. They belong to the family of Wiskott-Aldrich homology region-2 (WH2) proteins, which are involved in actin organization (Kerkhoff et al., 2001 [PubMed 11747823]).[supplied by OMIM].
Background References:
  • Rose, J. Phd, et al. Mol. Med. (2010) In press :
  • Pechlivanis, M., et al. J. Biol. Chem. 284(37):25324-25333(2009)
  • Bosch, M., et al. Mol. Cell 28(4):555-568(2007)
  • Ewing, R.M., et al. Mol. Syst. Biol. 3, 89 (2007) :
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Homology:
Predicted species reactivity based on immunogen sequence: Monkey, Mouse
Immunogen:
This SPIRE1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 665-691 amino acids from the C-terminal region of human SPIRE1.
NCBI Gene ID #:
56907
NCBI Official Name:
Protein spire homolog 1
NCBI Official Symbol:
SPIRE1
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
86 kDa
Protein Accession #:
Q08AE8
Protein GI Number:
425906061
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Research Area:
Signal Transduction
Swissprot #:
Q08AE8
User NOte:
Optimal dilutions for each application to be determined by the researcher.