ProSci

SNX13 Antibody

Product Code:
 
PSI-56-298
Product Group:
 
Primary Antibodies
Supplier:
 
ProSci
Host Type:
 
Rabbit
Antibody Isotype:
 
Rabbit Ig
Antibody Clonality:
 
Polyclonal
Regulatory Status:
 
RUO
Target Species:
 
Human
Application:
 
Western Blot (WB)
Storage:
 
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
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Western Blot at 1:1000 dilution + Hela whole cell lysate Lysates/proteins at 20 ug per lane.
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Western Blot at 1:1000 dilution + Hela whole cell lysate Lysates/proteins at 20 ug per lane.

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PSI-56-298-400ul400ul£626.00
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Further Information

Additional Names:
Sorting nexin-13, RGS domain- and PHOX domain-containing protein, RGS-PX1, SNX13, KIAA0713
Application Note:
For WB starting dilution is: 1:1000
Background:
This gene encodes a PHOX domain- and RGS domain-containing protein that belongs to the sorting nexin (SNX) family and the regulator of G protein signaling (RGS) family. The PHOX domain is a phosphoinositide binding domain, and the SNX family members are involved in intracellular trafficking. The RGS family members are regulatory molecules that act as GTPase activating proteins for G alpha subunits of heterotrimeric G proteins. The RGS domain of this protein interacts with G alpha(s), accelerates its GTP hydrolysis, and attenuates G alpha(s)-mediated signaling. Overexpression of this protein delayes lysosomal degradation of the epidermal growth factor receptor. Because of its bifunctional role, this protein may link heterotrimeric G protein signaling and vesicular trafficking.
Background References:
  • Rose, J. Phd, et al. Mol. Med. (2010) In press :
  • Hillman, R.T., et al. Genome Biol.(2), R8 (2004) :
  • Worby, C.A., et al. Nat. Rev. Mol. Cell Biol. 3(12):919-931(2002)
  • Kosan, C., et al. Cytogenet. Genome Res. 97 (3-4), 167-170 (2002) :
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Homology:
Predicted species reactivity based on immunogen sequence: Mouse
Immunogen:
This SNX13 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 780-807 amino acids from the C-terminal region of human SNX13.
NCBI Gene ID #:
23161
NCBI Official Name:
Sorting nexin-13
NCBI Official Symbol:
SNX13
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
112 kDa
Protein Accession #:
Q9Y5W8
Protein GI Number:
24418867
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Research Area:
Signal Transduction
Swissprot #:
Q9Y5W8
User NOte:
Optimal dilutions for each application to be determined by the researcher.