ProSci

SEC23IP Antibody

Product Code:
 
PSI-57-779
Product Group:
 
Primary Antibodies
Supplier:
 
ProSci
Host Type:
 
Rabbit
Antibody Isotype:
 
Rabbit Ig
Antibody Clonality:
 
Polyclonal
Regulatory Status:
 
RUO
Target Species:
 
Human
Application:
 
Western Blot (WB)
Storage:
 
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
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Western blot analysis in A549 cell line lysates (35ug/lane).
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Western blot analysis in A549 cell line lysates (35ug/lane).

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PSI-57-779-400ul400ul£626.00
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Further Information

Additional Names:
SEC23-interacting protein, p125, SEC23IP
Application Note:
For WB starting dilution is: 1:1000
Background:
COPII-coated vesicles are involved in protein transport from the endoplasmic reticulum to the Golgi apparatus. The protein encoded by this gene was identified by its interaction with a mouse protein similar to yeast Sec23p, an essential component of the COPII. This protein shares significant similarity with phospholipid-modifying proteins, especially phosphatidic acid preferring-phospholipase A1. Overexpression of this protein has been shown to cause disorganization of the endoplasmic reticulum-Golgi intermediate compartment and Golgi apparatus, which suggests its role in the early secretory pathway. [provided by RefSeq].
Background References:
  • Ong, Y.S., et al. J. Cell Biol. 190(3):331-345(2010)
  • Trynka, G., et al. Gut 58(8):1078-1083(2009)
  • Li, H., et al. J. Biol. Chem. 281(21):14748-14755(2006)
  • Grupe, A., et al. Am. J. Hum. Genet. 78(1):78-88(2006)
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
This SEC23IP antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 724-752 amino acids from the C-terminal region of human SEC23IP.
NCBI Gene ID #:
11196
NCBI Official Name:
SEC23-interacting protein
NCBI Official Symbol:
SEC23IP
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
111 kDa
Protein Accession #:
Q9Y6Y8
Protein GI Number:
55584014
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Research Area:
Signal Transduction
Swissprot #:
Q9Y6Y8
User NOte:
Optimal dilutions for each application to be determined by the researcher.