Further Information
Long-chain-fatty-acid--CoA ligase 3, Long-chain acyl-CoA synthetase 3, LACS 3, ACSL3, ACS3, FACL3, LACS3
For WB starting dilution is: 1:1000
The protein encoded by this gene is an isozyme of the
long-chain fatty-acid-coenzyme A ligase family. Although differing
in substrate specificity, subcellular localization, and tissue
distribution, all isozymes of this family convert free long-chain
fatty acids into fatty acyl-CoA esters, and thereby play a key role
in lipid biosynthesis and fatty acid degradation. This isozyme is
highly expressed in brain, and preferentially utilizes myristate,
arachidonate, and eicosapentaenoate as substrates. The amino acid
sequence of this isozyme is 92% identical to that of rat homolog.
Two transcript variants encoding the same protein have been found
for this gene.
- Weedon-Fekjaer, M.S., et al. J. Lipid Res. 51(7):1886-1896(2010)
- Cao, A., et al. J. Biol. Chem. 285(22):16664-16674(2010)
- Perera, F., et al. PLoS ONE(2), E4488 (2009) :
- Yao, H., et al. J. Biol. Chem. 283(2):849-854(2008)
Supplied in PBS with 0.09% (W/V) sodium azide.
batch dependent
Unconjugated
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Predicted species reactivity based on immunogen sequence: Rat
This ACSL3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 528-556 amino acids from the C-terminal region of human ACSL3.
2181
Long-chain-fatty-acid--CoA ligase 3
ACSL3
Homo sapiens
Liquid
PREDICTED MOLECULAR WEIGHT:
80 kDa
O95573
This antibody is purified through a protein A column, followed by peptide affinity purification.
Obesity,Signal Transduction
O95573
Optimal dilutions for each application to be determined by the researcher.