Further Information
N-alpha-acetyltransferase 10, 2.3.1.-, 2.3.1.88, N-terminal acetyltransferase complex ARD1 subunit homolog A, NatA catalytic subunit Naa10, NAA10, ARD1, ARD1A, TE2
For WB starting dilution is: 1:2000
Catalytic subunit of the N-terminal acetyltransferase A (NatA) complex which displays alpha (N-terminal) acetyltransferase activity. The NAT activity may be important for vascular, hematopoietic and neuronal growth and development. Without NAA15, displays epsilon (internal) acetyltransferase activity towards HIF1A, thereby promoting its degradation. Represses MYLK kinase activity by acetylation, and thus represses tumor cell migration. Acetylates, and stabilizes TSC2, thereby repressing mTOR activity and suppressing cancer development.
- Tribioli C.,et al.Hum. Mol. Genet. 3:1061-1068(1994).
- Arnesen T.,et al.Biochem. J. 386:433-443(2005).
- Ross M.T.,et al.Nature 434:325-337(2005).
- Mural R.J.,et al.Submitted (SEP-2005) to the EMBL/GenBank/DDBJ databases.
Supplied in PBS with 0.09% (W/V) sodium azide.
batch dependent
Unconjugated
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Predicted species reactivity based on immunogen sequence: Bovine, Mouse
This NAA10 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 135-167 amino acids from the Central region of human NAA10.
8260
N-alpha-acetyltransferase 10
NAA10
Homo sapiens
Liquid
PREDICTED MOLECULAR WEIGHT:
26 kDa
P41227
728880
This antibody is purified through a protein A column, followed by peptide affinity purification.
Obesity,Signal Transduction
P41227
Optimal dilutions for each application to be determined by the researcher.