ProSci

SLC24A3 Antibody

Product Code:
 
PSI-58-449
Product Group:
 
Primary Antibodies
Supplier:
 
ProSci
Host Type:
 
Rabbit
Antibody Isotype:
 
Rabbit Ig
Antibody Clonality:
 
Polyclonal
Regulatory Status:
 
RUO
Target Species:
 
Human
Application:
 
Western Blot (WB)
Storage:
 
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
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Western blot analysis in MCF-7 cell line lysates (35ug/lane).
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Western blot analysis in MCF-7 cell line lysates (35ug/lane).

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PSI-58-449-400ul400ul£626.00
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Further Information

Additional Names:
Sodium/potassium/calcium exchanger 3, Na(+)/K(+)/Ca(2+)-exchange protein 3, Solute carrier family 24 member 3, SLC24A3, NCKX3
Application Note:
For WB starting dilution is: 1:1000
Background:
Plasma membrane sodium/calcium exchangers are an important component of intracellular calcium homeostasis and electrical conduction. Potassium-dependent sodium/calcium exchangers such as SLC24A3 are believed to transport 1 intracellular calcium and 1 potassium ion in exchange for 4 extracellular sodium ions (Kraev et al., 2001 [PubMed 11294880]).
Background References:
  • Rose, J.E., et al. Mol. Med. 16 (7-8), 247-253 (2010) :
  • Cheng, Y.C., et al. Circ Cardiovasc Genet 2(4):329-337(2009)
  • Deloukas, P., et al. Nature 414(6866):865-871(2001)
  • Kraev, A., et al. J. Biol. Chem. 276(25):23161-23172(2001)
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
This SLC24A3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 79-108 amino acids from the N-terminal region of human SLC24A3.
NCBI Gene ID #:
57419
NCBI Official Name:
Sodium/potassium/calcium exchanger 3
NCBI Official Symbol:
SLC24A3
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
72 kDa
Protein Accession #:
Q9HC58
Protein GI Number:
116242671
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Research Area:
Obesity,Signal Transduction
Swissprot #:
Q9HC58
User NOte:
Optimal dilutions for each application to be determined by the researcher.