ProSci

CBR4 Antibody

Product Code:
 
PSI-59-253
Product Group:
 
Primary Antibodies
Supplier:
 
ProSci
Host Type:
 
Rabbit
Antibody Isotype:
 
Rabbit Ig
Antibody Clonality:
 
Polyclonal
Regulatory Status:
 
RUO
Target Species:
 
Human
Application:
 
Western Blot (WB)
Storage:
 
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
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Western blot analysis in ZR-75-1 cell line lysates (35ug/lane).
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Western blot analysis in ZR-75-1 cell line lysates (35ug/lane).

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PSI-59-253-400ul400ul£626.00
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Further Information

Additional Names:
Carbonyl reductase family member 4, 1---, 3-oxoacyl-[acyl-carrier-protein] reductase, 111-, Quinone reductase CBR4, CBR4
Application Note:
For WB starting dilution is: 1:1000
Background:
The heteroteramer with HSD17B8 has NADH-dependent 3-ketoacyl-acyl carrier protein reductase activity. May play a role in biosynthesis of fatty acids in mitochondria. The homotetramer may act as NADPH-dependent quinone reductase. Has broad substrate specificity and reduces 9,10-phenanthrenequinone, 1,4-benzoquinone and various other o-quinones and p-quinones (in vitro).
Background References:
  • Chen, Z., et al. FASEB J. 23(11):3682-3691(2009)
  • Persson, B., et al. Chem. Biol. Interact. 178 (1-3), 94-98 (2009) :
  • Endo, S., et al. Biochem. Biophys. Res. Commun. 377(4):1326-1330(2008)
  • Lamesch, P., et al. Genomics 89(3):307-315(2007)
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
This CBR4 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 178-205 amino acids from the C-terminal region of human CBR4.
NCBI Gene ID #:
84869
NCBI Official Name:
Carbonyl reductase family member 4
NCBI Official Symbol:
CBR4
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
25 kDa
Protein Accession #:
Q8N4T8
Protein GI Number:
269849708
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Research Area:
Obesity,Signal Transduction
Swissprot #:
Q8N4T8
User NOte:
Optimal dilutions for each application to be determined by the researcher.