ProSci

TRPV5 Antibody

Product Code:
 
PSI-58-706
Product Group:
 
Primary Antibodies
Supplier:
 
ProSci
Host Type:
 
Rabbit
Antibody Isotype:
 
Rabbit Ig
Antibody Clonality:
 
Polyclonal
Regulatory Status:
 
RUO
Target Species:
 
Human
Application:
 
Western Blot (WB)
Storage:
 
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
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Western blot analysis in HepG2 cell line lysates (35ug/lane).
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Western blot analysis in HepG2 cell line lysates (35ug/lane).

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PSI-58-706-400ul400ul£626.00
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Further Information

Additional Names:
Transient receptor potential cation channel subfamily V member 5, TrpV5, Calcium transport protein 2, CaT2, Epithelial calcium channel 1, ECaC, ECaC1, Osm-9-like TRP channel 3, OTRPC3, TRPV5, ECAC1
Application Note:
For WB starting dilution is: 1:1000
Background:
This gene is a member of the transient receptor family and the TrpV subfamily. The calcium-selective channel encoded by this gene has 6 transmembrane-spanning domains, multiple potential phosphorylation sites, an N-linked glycosylation site, and 5 ANK repeats. This protein forms homotetramers or heterotetramers and is activated by a low internal calcium level.
Background References:
  • Chamoux, E., et al. J. Biol. Chem. 285(33):25354-25362(2010)
  • Kennedy, B.G., et al. Mol. Vis. 16, 665-675 (2010) :
  • Yerges, L.M., et al. J. Bone Miner. Res. 24(12):2039-2049(2009)
  • de Groot, T., et al. J. Am. Soc. Nephrol. 20(8):1693-1704(2009)
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
This TRPV5 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 634-663 amino acids from the C-terminal region of human TRPV5.
NCBI Gene ID #:
56302
NCBI Official Name:
Transient receptor potential cation channel subfamily V member 5
NCBI Official Symbol:
TRPV5
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
83 kDa
Protein Accession #:
Q9NQA5
Protein GI Number:
62901471
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Research Area:
Obesity,Signal Transduction
Swissprot #:
Q9NQA5
User NOte:
Optimal dilutions for each application to be determined by the researcher.