ProSci

TRMU Antibody

Product Code:
 
PSI-60-317
Product Group:
 
Primary Antibodies
Supplier:
 
ProSci
Host Type:
 
Rabbit
Antibody Isotype:
 
Rabbit Ig
Antibody Clonality:
 
Polyclonal
Regulatory Status:
 
RUO
Target Species:
 
Human
Application:
 
Western Blot (WB)
Storage:
 
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
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Western blot analysis in MDA-MB453 cell line lysates (35ug/lane).
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Western blot analysis in MDA-MB453 cell line lysates (35ug/lane).

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PSI-60-317-400ul400ul£626.00
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Further Information

Additional Names:
Mitochondrial tRNA-specific 2-thiouridylase 1, 281-, MTO2 homolog, TRMU, MTU1, TRMT1
Application Note:
For WB starting dilution is: 1:1000
Background:
This gene is a member of the trmU family. It encodes a mitochondria-specific tRNA-modifying enzyme that is required for the 2-thio modification of 5-taurinomethyl-2-thiouridine tRNA-Lys on the wobble position of the anticodon.
Background References:
  • Zeharia, A., et al. Am. J. Hum. Genet. 85(3):401-407(2009)
  • Reiling, E., et al. Eur. J. Hum. Genet. 17(8):1056-1062(2009)
  • de Moraes, V.C., et al. Biochem. Biophys. Res. Commun. 381(2):210-213(2009)
  • Otaegui, D., et al. Audiol. Neurootol. 13(5):320-327(2008)
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
This TRMU antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 128-154 amino acids from the Central region of human TRMU.
NCBI Gene ID #:
55687
NCBI Official Name:
Mitochondrial tRNA-specific 2-thiouridylase 1
NCBI Official Symbol:
TRMU
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
48 kDa
Protein Accession #:
O75648
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Research Area:
Obesity
Swissprot #:
O75648
User NOte:
Optimal dilutions for each application to be determined by the researcher.