ProSci

P2RX6 Antibody

Product Code:
 
PSI-58-955
Product Group:
 
Primary Antibodies
Supplier:
 
ProSci
Host Type:
 
Rabbit
Antibody Isotype:
 
Rabbit Ig
Antibody Clonality:
 
Polyclonal
Regulatory Status:
 
RUO
Target Species:
 
Human
Application:
 
Western Blot (WB)
Storage:
 
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
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Western blot analysis in 293 cell line lysates (35ug/lane).
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Western blot analysis in 293 cell line lysates (35ug/lane).

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PSI-58-955-400ul400ul£626.00
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Further Information

Additional Names:
P2X purinoceptor 6, P2X6, ATP receptor, P2XM, Purinergic receptor, Purinergic receptor P2X-like 1, P2RX6, P2RXL1, P2X6
Application Note:
For WB starting dilution is: 1:1000
Background:
The protein encoded by this gene belongs to the family of P2X receptors, which are ATP-gated ion channels and mediate rapid and selective permeability to cations. This gene is predominantly expressed in skeletal muscle, and regulated by p53. The encoded protein is associated with VE-cadherin at the adherens junctions of human umbilical vein endothelial cells. Alternative splicing results in multiple transcript variants. A related pseudogene, which is also located on chromosome 22, has been identified.
Background References:
  • Trynka, G., et al. Gut 58(8):1078-1083(2009)
  • Luke, M.M., et al. Stroke 40(2):363-368(2009)
  • Palomino-Doza, J., et al. Hypertension 52(5):980-985(2008)
  • Shiffman, D., et al. Arterioscler. Thromb. Vasc. Biol. 28(1):173-179(2008)
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
This P2RX6 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 198-226 amino acids from the Central region of human P2RX6.
NCBI Gene ID #:
9127
NCBI Official Name:
P2X purinoceptor 6
NCBI Official Symbol:
P2RX6
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
49 kDa
Protein Accession #:
O15547
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Research Area:
Neuroscience,Signal Transduction
Swissprot #:
O15547
User NOte:
Optimal dilutions for each application to be determined by the researcher.