Further Information
Dynein intermediate chain 1, axonemal, Axonemal dynein intermediate chain 1, DNAI1
For WB starting dilution is: 1:1000
The inner- and outer-arm dyneins, which bridge between the
doublet microtubules in axonemes, are the force-generating proteins
responsible for the sliding movement in axonemes. The intermediate
and light chains, thought to form the base of the dynein arm, help
mediate attachment and may also participate in regulating dynein
activity. This gene encodes an intermediate chain dynein, belonging
to the large family of motor proteins. Mutations in this gene
result in abnormal ciliary ultrastructure and function associated
with primary ciliary dyskinesia (PCD) and Kartagener syndrome.
- Rose, J.E., et al. Mol. Med. 16 (7-8), 247-253 (2010) :
- Leigh, M.W., et al. Curr. Opin. Pediatr. 21(3):320-325(2009)
- Zuccarello, D., et al. Hum. Reprod. 23(8):1957-1962(2008)
- Failly, M., et al. Respiration 76(2):198-204(2008)
Supplied in PBS with 0.09% (W/V) sodium azide.
batch dependent
Unconjugated
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Predicted species reactivity based on immunogen sequence: Bovine, Mouse, Rat
This DNAI1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 92-120 amino acids from the N-terminal region of human DNAI1.
27019
Dynein intermediate chain 1, axonemal
DNAI1
Homo sapiens
Liquid
PREDICTED MOLECULAR WEIGHT:
79 kDa
Q9UI46
12643888
This antibody is purified through a protein A column, followed by peptide affinity purification.
Neuroscience,Signal Transduction
Q9UI46
Optimal dilutions for each application to be determined by the researcher.