ProSci

NR2E1 Antibody

Product Code:
 
PSI-60-773
Product Group:
 
Primary Antibodies
Supplier:
 
ProSci
Host Type:
 
Rabbit
Antibody Isotype:
 
Rabbit Ig
Antibody Clonality:
 
Polyclonal
Regulatory Status:
 
RUO
Target Species:
 
Human
Application:
 
Western Blot (WB)
Storage:
 
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
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Western blot analysis in HL-60 cell line lysates (35ug/lane).
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Western blot analysis in HL-60 cell line lysates (35ug/lane).

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PSI-60-773-400ul400ul£626.00
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Further Information

Additional Names:
Nuclear receptor subfamily 2 group E member 1, Nuclear receptor TLX, Protein tailless homolog, Tll, hTll, NR2E1, TLX
Application Note:
For WB starting dilution is: 1:1000
Background:
Orphan receptor that binds DNA as a monomer to hormone response elements (HRE) containing an extended core motif half-site sequence 5'-AAGGTCA-3' in which the 5' flanking nucleotides participate in determining receptor specificity. May be required for brain development. May be involved in the regulation of retinal development (By similarity).
Background References:
  • Liu, H.K., et al. Genes Dev. 24(7):683-695(2010)
  • Iwahara, N., et al. Biochem. Biophys. Res. Commun. 386(4):671-675(2009)
  • de Krom, M., et al. Biol. Psychiatry 65(7):625-630(2009)
  • Kumar, R.A., et al. Am. J. Med. Genet.Neuropsychiatr. Genet. 147B (6), 880-889 (2008) :
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Homology:
Predicted species reactivity based on immunogen sequence: Chicken, Mouse, Xenopus
Immunogen:
This NR2E1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 75-102 amino acids from the Central region of human NR2E1.
NCBI Gene ID #:
7101
NCBI Official Name:
Nuclear receptor subfamily 2 group E member 1
NCBI Official Symbol:
NR2E1
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
43 kDa
Protein Accession #:
Q9Y466
Protein GI Number:
9910804
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Research Area:
Neuroscience,Signal Transduction
Swissprot #:
Q9Y466
User NOte:
Optimal dilutions for each application to be determined by the researcher.