Further Information
Interleukin-1 receptor type 1, IL-1R-1, IL-1RT-1, IL-1RT1, CD121 antigen-like family member A, Interleukin-1 receptor alpha, IL-1R-alpha, Interleukin-1 receptor type I, p80, CD121a, Interleukin-1 receptor type 1, membrane form, mIL-1R1, mIL-1RI, Interleukin-1 receptor type 1, soluble form, sIL-1R1, sIL-1RI, IL1R1, IL1R, IL1RA, IL1RT1
For WB starting dilution is: 1:1000
For IHC-P starting dilution is: 1:10~50
IL1R is a member of the interleukin 1 receptor family. An experiment with transient gene expression demonstrated that this receptor was incapable of binding to interleukin 1 alpha and interleukin 1 beta with high affinity. IL1R is a receptor for interleukin 1 family member 9 (IL1F9). Binding to the agonist leads to the activation of NF-kappa-B. The gene for this protein and four other interleukin 1 receptor family genes, including interleukin 1 receptor, type I (IL1R1), interleukin 1 receptor, type II (IL1R2), interleukin 1 receptor-like 1 (IL1RL1), and interleukin 18 receptor 1 (IL18R1), form a cytokine receptor gene cluster in a region mapped to chromosome 2q12.
- Debets, R., et al., J. Immunol. 167(3):1440-1446 (2001).
- Dale, M., et al., Genomics 57(1):177-179 (1999).
- Torigoe, K., et al., J. Biol. Chem. 272(41):25737-25742 (1997).
- Lovenberg, T.W., et al., J. Neuroimmunol. 70(2):113-122 (1996).
Supplied in PBS with 0.09% (W/V) sodium azide.
batch dependent
Unconjugated
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Predicted species reactivity based on immunogen sequence: Rat
This IL1R antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 474-503 amino acids from the C-terminal region of human IL1R.
3554
Interleukin-1 receptor type 1
IL1R1
Homo sapiens
Liquid
PREDICTED MOLECULAR WEIGHT:
65 kDa
P14778
124308
This antibody is purified through a protein A column, followed by peptide affinity purification.
Immunology,Signal Transduction
P14778
Optimal dilutions for each application to be determined by the researcher.