Further Information
T-complex protein 1 subunit eta, TCP-1-eta, CCT-eta, HIV-1 Nef-interacting protein, CCT7, CCTH, NIP7-1
For WB starting dilution is: 1:1000
This gene encodes a molecular chaperone that is a member
of the chaperonin containing TCP1 complex (CCT), also known as the
TCP1 ring complex (TRiC). This complex consists of two identical
stacked rings, each containing eight different proteins. Unfolded
polypeptides enter the central cavity of the complex and are folded
in an ATP-dependent manner. The complex folds various proteins,
including actin and tubulin. Alternative splicing results in
multiple transcript variants. Related pseudogenes have been
identified on chromosomes 5 and 6.
- Mukherjee, K., et al. BMC Evol. Biol. 10, 64 (2010) :
- Zebol, J.R., et al. Int. J. Biochem. Cell Biol. 41(4):822-827(2009)
- Guo, D., et al. Biochem. Biophys. Res. Commun. 337(4):1308-1318(2005)
- Hanafy, K.A., et al. J. Biol. Chem. 279(45):46946-46953(2004)
Supplied in PBS with 0.09% (W/V) sodium azide.
batch dependent
Unconjugated
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Predicted species reactivity based on immunogen sequence: Bovine, Chicken, Mouse
This CCT7 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 64-92 amino acids from the N-terminal region of human CCT7.
10574
T-complex protein 1 subunit eta
CCT7
Homo sapiens
Liquid
PREDICTED MOLECULAR WEIGHT:
59 kDa
Q99832
3041738
This antibody is purified through a protein A column, followed by peptide affinity purification.
Immunology,Signal Transduction
Q99832
Optimal dilutions for each application to be determined by the researcher.