ProSci

RALBP1 Antibody

Product Code:
 
PSI-60-516
Product Group:
 
Primary Antibodies
Supplier:
 
ProSci
Host Type:
 
Rabbit
Antibody Isotype:
 
Rabbit Ig
Antibody Clonality:
 
Polyclonal
Regulatory Status:
 
RUO
Target Species:
 
Human
Application:
 
Western Blot (WB)
Storage:
 
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
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Western blot analysis in MCF-7 cell line lysates (35ug/lane).

Western blot analysis in MCF-7 cell line lysates (35ug/lane).

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PSI-60-516-400ul400ul£626.00
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Further Information

Additional Names:
RalA-binding protein 1, RalBP1, 76 kDa Ral-interacting protein, Dinitrophenyl S-glutathione ATPase, DNP-SG ATPase, Ral-interacting protein 1, RALBP1, RLIP1, RLIP76
Application Note:
For WB starting dilution is: 1:1000
Background:
RALBP1 plays a role in receptor-mediated endocytosis and is a downstream effector of the small GTP-binding protein RAL (see RALA; MIM 179550). Small G proteins, such as RAL, have GDP-bound inactive and GTP-bound active forms, which shift from the inactive to the active state through the action of RALGDS (MIM 601619), which in turn is activated by RAS (see HRAS; MIM 190020) (summary by Feig, 2003 [PubMed 12888294]).
Background References:
  • Singhal, S.S., et al. Int. J. Cancer 126(6):1327-1338(2010)
  • Singhal, S.S., et al. Cancer Lett. 283(2):152-158(2009)
  • Awasthi, Y.C., et al.Toxicol Environ HealthCrit Rev 12(7):540-551(2009)
  • Singhal, S.S., et al. Cancer Res. 69(10):4244-4251(2009)
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
This RALBP1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 42-71 amino acids from the N-terminal region of human RALBP1.
NCBI Gene ID #:
10928
NCBI Official Name:
RalA-binding protein 1
NCBI Official Symbol:
RALBP1
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
76 kDa
Protein Accession #:
Q15311
Protein GI Number:
34098413
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Research Area:
Cell Cycle,Immunology,Signal Transduction
Swissprot #:
Q15311
User NOte:
Optimal dilutions for each application to be determined by the researcher.