ProSci

DKK1 Antibody

Product Code:
 
PSI-64-019
Product Group:
 
Primary Antibodies
Supplier:
 
ProSci
Host Type:
 
Rabbit
Antibody Isotype:
 
Rabbit Ig
Antibody Clonality:
 
Polyclonal
Regulatory Status:
 
RUO
Target Species:
 
Human
Application:
 
Western Blot (WB)
Storage:
 
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
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Western blot analysis of DKK1 Antibody in T47D cell line lysates (35ug/lane)
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Western blot analysis of DKK1 Antibody in T47D cell line lysates (35ug/lane)

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PSI-64-019-400ul400ul£626.00
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Further Information

Additional Names:
Dickkopf-related protein 1, Dickkopf-1, Dkk-1, hDkk-1, SK, DKK1
Application Note:
For WB starting dilution is: 1:1000
Background:
DKK1 is a protein that is a member of the dickkopf family. It is a secreted protein with two cysteine rich regions and is involved in embryonic development through its inhibition of the WNT signaling pathway. Elevated levels of DKK1 in bone marrow plasma and peripheral blood is associated with the presence of osteolytic bone lesions in patients with multiple myeloma.
Background References:
  • Piters, E., et al. Calcif. Tissue Int. 86(4):271-281(2010)
  • Bourhis, E., et al. J. Biol. Chem. 285(12):9172-9179(2010)
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
This DKK1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 58-84 amino acids from the N-terminal region of human DKK1.
NCBI Gene ID #:
22943
NCBI Official Name:
Dickkopf-related protein 1
NCBI Official Symbol:
DKK1
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
29 kDa
Protein Accession #:
O94907
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Research Area:
Cell Cycle,Immunology,Signal Transduction
Swissprot #:
O94907
User NOte:
Optimal dilutions for each application to be determined by the researcher.